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首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Use of balloon expandable transcatheter valves for valve-in-valve implantation in patients with degenerative stentless aortic bioprostheses: Technical considerations and results
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Use of balloon expandable transcatheter valves for valve-in-valve implantation in patients with degenerative stentless aortic bioprostheses: Technical considerations and results

机译:气囊膨胀式经导管瓣膜在无变性无支架主动脉生物假体患者中的瓣膜植入中的应用:技术考虑和结果

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Objective Transcatheter valve-in-valve is an accepted treatment in high-risk patients with degenerative stented bioprostheses in the aortic position. Experience in treating stentless valves is, however, limited. Our aim was to determine the feasibility and single-center outcome of balloon expandable SAPIEN valve placement in degenerated stentless aortic valve bioprostheses. Methods From February 2010 to January 2014, 10 patients with failing stentless bioprostheses underwent transcatheter aortic valve implantation using the Edwards SAPIEN transcatheter heart valve (SAPIEN, SAPIEN XT, and SAPIEN 3) at our institution. Seven patients had valve failure due to regurgitation and three to stenosis. The mean age was 73.3 ± 15.0 years. The mean logistic EuroSCORE was 31.8 ± 20.3, and the Society of Thoracic Surgeons score was 7.6 ± 5.4. Results Technical success was achieved in 9 of 10 patients. One patient required immediate placement of a second valve owing to low placement of the first. Two intraoperative complications developed that needed additional procedures. One patient underwent immediate repair of a right ventricular perforation from a pacing lead, the other, reexploration for epicardial bleeding. No deaths occurred. The median length of stay was 8.5 days (range, 3-44). The mean follow-up was 8.1 months (range, 1-21). No late reoperations or reinterventions were required. Conclusions Transcatheter aortic valve implantation after previous stentless aortic valve replacement is technically demanding but a safe and feasible approach. The early results were excellent, with consistent improvement in hemodynamics. Prospective long-term follow-up in larger series is needed to evaluate this technique further.
机译:目的经导管瓣膜瓣膜瓣置换术是高危患者在主动脉位置进行变性支架植入生物假体的一种公认治疗方法。但是,治疗无支架瓣膜的经验有限。我们的目的是确定球囊扩张式SAPIEN瓣膜在退化的无支架主动脉瓣生物假体中的可行性和单中心结果。方法从2010年2月至2014年1月,在我们机构使用Edwards SAPIEN经导管心脏瓣膜(SAPIEN,SAPIEN XT和SAPIEN 3)对10例无支架生物假体失败的患者进行经导管主动脉瓣植入术。七名患者因反流导致瓣膜衰竭,三名因狭窄而出现瓣膜衰竭。平均年龄为73.3±15.0岁。 Logistic EuroSCORE的平均得分为31.8±20.3,胸外科医师协会得分为7.6±5.4。结果10例患者中有9例获得了技术成功。由于第一个瓣膜的位置低,一个病人需要立即放置第二个瓣膜。发生了两种术中并发症,需要额外的程序。一名患者使用起搏导线立即修复了右心室穿孔,另一例接受了心外膜出血的再探查。没有死亡发生。中位住院时间为8.5天(范围3-44)。平均随访时间为8.1个月(范围1-21)。无需后期重新手术或重新干预。结论先前无支架主动脉瓣置换后经导管主动脉瓣植入术对技术要求很高,但安全可行。早期结果非常好,血液动力学不断改善。需要大范围的前瞻性长期随访,以进一步评估该技术。

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