Stereoselective Synthesis of(E)-and(Z)-Fluoroalkenylboronates Using 2-Fluoroalkylideneiodonium Ylides Generated from(2-Fluoro-1-alkenyl)iodonium Salts

摘要

(E)-and(Z)-(fluoroalkenyl)boronates were prepared stereospecifically by the reaction of 2-fiuoroalky-lideneiodonium ylide generated from(E)-or(Z)-(2-fluoroalkenyl)iodonium salts with di(p-fluorophenoxy)-alkylboranes,followed by transesterification to pinacol esters.The resulting pinacol esters of(fluoroalkenyl)boranes were used for the stereoselective synthesis of trisubstituted fluoroalkenes by cross-coupling reactions.