The learning curve for successful radical prostatectomy (in terms of preventing prostate cancer recurrence) is steep and only begins to plateau when a surgeon has completed about 250 operations, according to a new study. Researchers calculated the effect of surgical experience on recurrence by reviewing records relating to 7,765 radical prostatectomies performed by 72 surgeons at four US centres between 1987 and 2003. Prostate cancer recurrence was defined as a serum prostate-specific antigen (PSA) level of 0.4 ng/ml or more, followed by a subsequent higher PSA level, after adjustment for established clinical and tumour characteristics.
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机译：根据一项新的研究，成功进行根治性前列腺切除术的学习曲线非常陡峭（就预防前列腺癌的复发而言），只有在外科医生完成约250例手术后才开始达到平稳状态。研究人员通过回顾1987年至2003年间美国四个中心的72位外科医生进行的7,765例根治性前列腺切除术的相关记录，计算了手术经验对复发的影响。前列腺癌的复发被定义为血清前列腺特异性抗原（PSA）的水平为0.4 ng /调整既定的临床和肿瘤特征后，每毫升或更多毫升，随后更高的PSA水平。
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