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A New Rumenic Acid Derivative from the Roots of Cudrania tricuspidata

机译:Cu木根的一种新的瘤胃酸衍生物

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摘要

A new rumenic acid derivative, threo-9,10-O-isopropylidene-13-hydroxy-(11E)-octadecenoic acid (1), and two known compounds, steppogenin (2) and oxyresveratrol (3), were isolated from the roots of Cudrania tricuspidata. The structure of the new compound was established by spectroscopic methods. All the compounds were evaluated for their cytotoxicity against three human tumor cell lines (HepG2, HCT-116, and SGC-7901). Unfortunately, none of them exhibited significant cytotoxicity at a concentration of 100 mu M.
机译:从根中分离出一种新的瘤胃酸衍生物threo-9,10-O-异亚丙基-13-羟基-(11E)-十八烯酸(1)和两种已知化合物steppogenin(2)和氧白藜芦醇(3)。 Cu草。通过光谱法确定了新化合物的结构。评估了所有化合物对三种人类肿瘤细胞系(HepG2,HCT-116和SGC-7901)的细胞毒性。不幸的是,它们在100μM的浓度下都没有表现出明显的细胞毒性。

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