Simultaneous occurrence of dermatomyositis and systemic sarcoidosis with recurrent breast cancer

摘要

Internal malignancy is one of the precipitating factors for both systemic sarcoidosis1 and dermatomyositis.2 Herein, we report a recurrence case of breast cancer who developed both diseases simultaneously. Of interest, treatment of the recurrent breast cancer reinforced the improvement of both disease manifestations.A 79-year-old woman was referred to our hospital for her facial and upper trunk erythema which were resistant to a conventional therapy including topical or oral steroid (prednisolone [PSL], 30 mg daily). Notably, at this time, the oral steroid was effective but it was not possible to reduce or quit PSL. These lesions had gradually become obvious after her breast cancer had recurred. As shown in Figure 1 (a), there were diffuse indurated placoid erythemas on her face and ear lobes, and edematous eyelids. Palm-sized scaly erythema was observed on her back (Fig. 1b). Although signs of myopathy were absent, clinically, we suspected her skin manifestations as those of dermatomyositis.