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Survey of community-associated methicillin-resistant Staphylococcus aureus in Korea-authors' response

机译:作者对韩国社区耐甲氧西林金黄色葡萄球菌的调查

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Sir,We thank Park et al. for their thoughtful comments on our study on community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Korea.2 We agree that our finding of multidrug-resistant (MDR) CA-MRSA should be interpreted with caution. When we re-analysed our data on antibiotic resistance according to the clinical significance of the CA-MRSA isolates, the MDR rate was 47% in the pathogen group, 38% in the colonizer group and 97% in the group of undetermined significance (Table 1). The rates of MDR were also very different depending on the sequence types (STs) of the CA-MRSA isolates. For instance, only 1 of 25 isolates of the ST72 clone was MDR, whereas all the isolates of the ST5 and ST239 clones were MDR. Of the 31 isolates of the staphylococ-cal cassette chromosome mec (SCCmec) IVa clone, 8 (26%) were MDR.
机译:主席先生,我们感谢Park等。他们对韩国社区耐甲氧西林金黄色葡萄球菌(CA-MRSA)的研究发表了有思想的评论。2我们同意谨慎对待多药耐药(MDR)CA-MRSA的发现。当我们根据CA-MRSA分离物的临床意义重新分析抗生素耐药性数据时,病原体组的MDR率为47%,定植者组的MDR率为38%,未定意义的组的MDR率为97%(表1)。根据CA-MRSA分离株的序列类型(ST),MDR的比率也存在很大差异。例如,ST72克隆的25个分离株中只有1个是MDR,而ST5和ST239克隆的所有分离株都是MDR。在葡萄球菌盒式染色体mec(SCCmec)IVa克隆的31种分离物中,有8种(26%)是MDR。

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