Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers

Rider Christopher F.; Yamamoto Masatsugu; Guenther Oliver P.; Hirota Jeremy A.; Singh Amrit; Tebbutt Scott J.; Carlsten Chris

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Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers

机译：受控的柴油机排气和过敏原共暴露可调节人类的microRNA和基因表达：对炎症性肺标志物的影响

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摘要

Background: Air pollution's association with asthma may be due to its augmentation of allergenic effects, but the role of microRNA (miRNA) and gene expression in this synergy is unknown.

机译：背景：空气污染与哮喘的关联可能是由于其增加了变应原作用，但在这种协同作用中微RNA（miRNA）和基因表达的作用尚不清楚。

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《The Journal of Allergy and Clinical Immunology》 |2016年第6期|共11页
作者
Rider Christopher F.; Yamamoto Masatsugu; Guenther Oliver P.; Hirota Jeremy A.; Singh Amrit; Tebbutt Scott J.; Carlsten Chris;
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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Air pollution; allergy; controlled human exposure; inflammatory markers; multi-omics;

机译：空气污染;过敏;可控制的人体暴露;炎症标志物;多组学;

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1. Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers [J] . Rider Christopher F., Yamamoto Masatsugu, Guenther Oliver P., The Journal of Allergy and Clinical Immunology . 2016,第6期

机译：受控的柴油机排气和过敏原共暴露可调节人类的microRNA和基因表达：对炎症性肺标志物的影响
2. Effects of Controlled Diesel Exhaust and Allergen Exposure on microRNA and Gene Expression in Humans Modulation of Lung Inflammatory Markers Associated with Asthma [J] . Rider Christopher F., Yamamoto Masatsugu, Gunther Oliver P., Annals of the American Thoracic Society . 2018,第Suppla2期

机译：控制柴油机排气和过敏原暴露对哮喘相关肺炎炎症标志物人体调节中的微小瘤和基因表达的影响
3. Inflammatory effects on human lung epithelial cells after exposure to diesel exhaust micron sub particles (PM_(1.0)) and pollen allergens [J] . G. Mazzarella, V. Esposito, A. Bianco, Environmental Pollution . 2012,第feba期

机译：暴露于柴油机排气微粒子颗粒（PM_（1.0））和花粉过敏原后对人肺上皮细胞的炎性作用
4. Toxicity of diesel engine exhausts: induction of a pro-inflammatory response and apoptosis in an in vitro model of lung slices in biphasic organotypic culture [C] . Elsa Le Prieur, Jean Paul Morin, Emmanuelle Vaz, SAE International Fuels and Lubricants Meeting and Exposition . 2001

机译：柴油发动机排气的毒性：双相有机型培养中肺切片体外模型中促炎反应和凋亡的诱导
5. MicroRNAs as modulators of the airway gene expression response to smoking and lung cancer [D] . Perdomo, Maria Catalina 2012

机译：MicroRNA作为调节剂对吸烟和肺癌的气道基因表达反应
6. Co-exposure to allergen and diesel exhaust enhance inflammatory responses in human airway submucosa [O] . Ali Hosseini, Tillie L Hackett, Jeremy Hirota, 2014

机译：共同暴露于过敏原和柴油机排气会增强人气道黏膜下层的炎症反应
7. Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers [O] . Christopher F. Rider, Masatsugu Yamamoto, Oliver P. Günther, 2016

机译：受控柴油气排气和过敏原椰子调节人类中的microRNA和基因表达：对炎症性肺标记的影响

Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers

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