MIXED ORGANOFLUORINE-ORGANOSILICON CHEMISTRY .6. SYNTHESIS OF GEM-DIFLUORO-C-GLYCOSIDES AND C-DISACCHARIDES FROM ACYLSILANES AND TRINUOROMETHYLTRIMETHYLSIIANE - AN EXPLORATORY STUDY

摘要

Difluoroenoxysilanes, prepared from acylsilanes and trifluoromethyltrimethylsilane under fluoride activation, were glycosylated by glucal to yield C-diflnoroglycosides with a difluoromethylene group in place of the anomeric oxygen. Application of this methodology to a xylose-derived acylsilane led to a C-difluorodisaccharide. Copyright (C) 1996 Published by Elsevier Science Ltd [References: 6]