Clinical Application of Cultured Autologous Human Auricular Chondrocytes with Autologous Serum for Cranibfacial or Nasal Augmentation and Repair

摘要

The authors have corrected various craniofa-cial contour deformities using tissue culture-expanded autogenous tissue. Their method involves obtaining small cartilage biopsy specimens, expanding the number of cells from the biopsy specimens in tissue culture, and injecting the expanded cells into the defect. The authors' initial clinical results Rising this procedure are impressive. In addition to effectively solving the clinical problem, their method has certain advantages over standard techniques. Starting with small cartilage biopsy specimens virtually eliminates donor-site morbidity. Because the reconstructive material comes from the host, problems related to alloplastic implants are avoided. The surgical technique is minimally invasive, thereby decreasing operative exposure and concomitant morbidity