Asymmetric hydrogenation of minimally functionalised terminal olefins: An alternative sustainable and direct strategy for preparing enantioenriched hydrocarbons

摘要

This account discusses the progress made in the asymmetric hydrogenation of minimally functionalised terminal olefins as a new, alternative, sustainable and direct strategy for preparing enantioenriched hydrocarbons. It discusses the latest development in catalyst design, from the initial discovery of lanthanide catalytic precursors, through the use of transition-metal/diphosphine- iminophosphorane precursors, to the successful iridium/P,N catalytic systems. Chiral hydrocarbons through hydrogenation: This minireview highlights the progress made in the preparation of chiral hydrocarbons through asymmetric hydrogenation of minimally functionalised terminal olefins (see scheme).