Quetiapine-induced hepatocellular damage.

摘要

TO THE EDITOR: Hepatotoxicity is a possible adverse reaction of antip-sychotics. The elevation of liver enzymes is usually reversible, but fatal hepatitis also exists. Among the second generation antipsychotics, hepatic adverse reactions related with clozap-ine, risperidone, and olanzapine have been found.1 Quetiaping-induced hepatotoxicity is relatively rare. Here we report a middle-aged woman, who showed hepatocellular damage associated with quetiapine treatment, and the liver profiles returned to normal range soon after switching to other antipsychotics.