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首页> 外文期刊>Poultry Science >Expression pattern of adipocyte fatty acid-binding protein gene in different tissues and its regulation of genes related to adipocyte differentiation in duck.
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Expression pattern of adipocyte fatty acid-binding protein gene in different tissues and its regulation of genes related to adipocyte differentiation in duck.

机译:鸭脂肪细胞脂肪酸结合蛋白基因在不同组织中的表达方式及其对鸭脂肪细胞分化相关基因的调控

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摘要

Abundance of duck adipocyte fatty acid-binding protein (A-FABP) mRNA was detected in this study by quantitative real-time PCR. The results showed that duck A-FABP gene was expressed in muscular tissues and many organs, except pancreas, lung, and kidney, and highly expressed in adipose tissues, especially in sebum. The expression of A-FABP and adipocyte differentiation-related genes was upregulated by oleic acid, and the A-FABP knockdown suppressed the oleic acid-stimulated expression of these genes in the cultured duck adipocytes, indicating A-FABP might play an important role in duck adipocyte differentiation.
机译:通过定量实时PCR检测鸭脂肪细胞脂肪酸结合蛋白(A-FABP)mRNA的丰度。结果表明,鸭A-FABP基因在胰腺,肺和肾等肌肉组织和许多器官中表达,在脂肪组织中尤其是皮脂中高表达。油酸上调了A-FABP和脂肪细胞分化相关基因的表达,而A-FABP敲低抑制了油酸刺激的鸭脂肪细胞中这些基因的表达,表明A-FABP可能在鸭脂肪细胞中起重要作用。鸭脂肪细胞分化。

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