APPLICATION OF COMBINATORIAL CHEMISTRY AND HIGH-THROUGHPUT METHODS IN THE SYNTHESES AND INVESTIGATIONS OF POLYMER MATERIALS

摘要

The paper is a literature review of the methods, applying the combinatorial chemistry (CombiChem) approach, concerning the polymer materials syntheses, especially polycondensation (Table 1), radical polymerization, controlled radical polymerization and ring opening polymerization ROP. The equipment used in CombiChem processes, i.e. conventional and microwave reactors (Table 2, Fig. 1) were discussed. The process of formation of virtual polymer libraries and the methods of purification, analyses and characterization of the products obtained were described. The present degree of CombiChem application in design and preparation of novel biodegradable polymer materials was evaluated.