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Timothy Lu,29: Engineering viruses to destroy biofilms

机译:Timothy Lu,29:工程病毒以破坏生物膜

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At Harvard Medical School, many of Timothy Lu's patients were being attacked by carpets of microbial goo. They had "really bad infections," Lu says. "Patients with cystic fibrosis, people getting infections in their catheters. All caused by biofilms."rnLu, who is now an assistant professor at MIT, began researching how to destroy biofilms. But unlike those who had previously attacked the problem, he took advantage of the new tools of synthetic biology. He engineered a type of virus, known as a phage, to destroy biofilms and sabotage their defenses against antibiotics.
机译:在哈佛医学院,卢武Tim的许多患者都被微生物黏性地毯所袭击。卢说,他们“确实感染严重”。 “患有囊性纤维化的患者,人们的导管受到感染。全部是由生物膜引起的。” rnLu,现在是麻省理工学院的助理教授,开始研究如何破坏生物膜。但是,与那些以前曾攻击过该问题的人不同,他利用了合成生物学的新工具。他设计了一种被称为噬菌体的病毒,以破坏生物膜并破坏其对抗生素的防御能力。

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  • 来源
    《Technology review》 |2010年第5期|P.62-63|共2页
  • 作者

    Carl Zimmer;

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  • 正文语种 eng
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