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The Bacteria Fight Back

机译:细菌反击

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An unfortunate statistical fluctuation. Maybe not. As Vance Fowler, an infectious-disease specialist at Duke University Medical Center in Durham, North Carolina, tells it, the first case appeared in early spring 2008: a 13-year-old girl whose bout with the flu evolved into a life-and-death struggle, still ongoing, with necrotizing pneumonia and a particularly pernicious strain of bacteria known as methi-cillin-resistant Staphylococcus aureus (MRSA). Should the girl survive, her life will be "forever changed," says Fowler, from pulmonary disease caused by the death of the lung tissue. The next case, a week or so later, was a research technician from Fowler's laboratory, admitted to the hospital with a facial abscess that showed no signs of healing. Again, MRSA was the cause. A week or so after that, the victims were a husband and wife. "Both were admitted with life-threatening acute MRSA infections out of nowhere," he says. "Multiple surgeries. Life- and limb-threatening infections." Neither one worked in a hospital or a long-term care facility, the kind of environments in which such bacteria might commonly be found. Nor had they visited one recently. So how did they get it? "Bad luck, bad genes, a bad bug, or all three," says Fowler.
机译:不幸的统计波动。也许不会。正如北卡罗来纳州达勒姆市杜克大学医学中心的传染病专家万斯·福勒(Vance Fowler)所说,第一例出现在2008年初春:一名13岁的女孩,因流感而患上了感冒, -死亡斗争,仍在继续,包括坏死性肺炎和一种特别有害的细菌菌株,称为耐甲氧西林的金黄色葡萄球菌(MRSA)。福勒说,如果女孩生存下来,她的生活将“永远改变”,这是由于肺组织死亡引起的肺部疾病。下一个病例,大约一周后,是福勒实验室的一名研究技术人员,因面部脓肿没有任何康复迹象而入院。同样,MRSA是原因。在那之后一周左右,受害者是一对夫妻。他说:“两人都被冒着生命危险的急性MRSA感染所接纳。” “多次手术。威胁生命和肢体的感染。”没有人在医院或长期护理机构中工作过,这种环境通常会发现这种细菌。他们最近也没有去过。那么他们是怎么得到的呢?福勒说:“运气不好,基因不好,虫子不好,或者这三个都不好。”

著录项

  • 来源
    《Science》 |2008年第5887期|p.356-361|共6页
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  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
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