Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor

Yanping Wang; Steven J. Marling; Jinge G. Zhu; Kyle S. Severson; Hector F. DeLuca

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Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor

机译：小鼠实验性自身免疫性脑脊髓炎（EAE）的发展需要维生素D和维生素D受体

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摘要

The development of experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis, has been studied in mice that were (ⅰ) vitamin D-deficient, (ⅱ) minus the vitamin D receptor, (ⅲ) minus a vitamin D 25-hydroxylase, and (ⅳ) minus the vitamin D 25-hydroxyvitamin D-1

机译：已在以下小鼠中研究了实验性自身免疫性脑脊髓炎（EAE）的发展：多发性硬化症模型，其中（vitamin）缺乏维生素D，（ⅱ）减去维生素D受体，（ⅲ）减去维生素D 25-羟化酶和（ⅳ）减去维生素D 25-羟基维生素D-1

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《Proceedings of the National Academy of Sciences of the United States of America》 |2012年第22期|p.8501-8504|共4页
作者
Yanping Wang; Steven J. Marling; Jinge G. Zhu; Kyle S. Severson; Hector F. DeLuca;
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作者单位

Department of Biochemistry, University of Wisconsin, Madison, Wl 53706;

Department of Biochemistry, University of Wisconsin, Madison, Wl 53706;

Department of Biochemistry, University of Wisconsin, Madison, Wl 53706;

Department of Biochemistry, University of Wisconsin, Madison, Wl 53706;

Department of Biochemistry, University of Wisconsin, Madison, Wl 53706;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
autoimmune disease; serum calcium; serum 25-hydroxyvitamin D3; CYP27B1 knockout mice; CYP2R1 knockout mice;

机译：自身免疫性疾病血清钙;血清25-羟基维生素D3;CYP27B1敲除小鼠;CYP2R1敲除小鼠;

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1. Serum levels of 25-hydroxy vitamin D in normal Biozzi and C57BL/6 mice and during the course of chronic relapsing experimental autoimmune encephalomyelitis (CR EAE) [J] . BoltonC., GatesJ., GiovannoniG. Inflammation research: Official journal of the European Histamine Research Society . 2013,第7期

机译：正常Biozzi和C57BL / 6小鼠以及慢性复发性实验性自身免疫性脑脊髓炎（CR EAE）过程中的血清25-羟基维生素D水平
2. Estrogen Controls Vitamin D3-Mediated Resistance to Experimental Autoimmune Encephalomyelitis by Controlling Vitamin D3 Metabolism and Receptor Expression [J] . Faye E. Nashold, Karen M. Spach, Justin A. Spanier, The journal of immunology . 2009,第6期

机译：雌激素通过控制维生素D3代谢和受体表达来控制维生素D3介导的对实验性自身免疫性脑脊髓炎的抵抗力。
3. The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: Evidence for the involvement of astrocytes [J] . DutraR.C., BentoA.F., LeiteD.F.P., Neurobiology of disease . 2013,第Null期

机译：激肽B1和B2受体在小鼠实验性自身免疫性脑脊髓炎（EAE）引起的持续性疼痛中的作用：星形胶质细胞参与的证据
4. Nanomaterials for immunotherapy against multiple sclerosis/experimental autoimmune encephalomyelitis (EAE) [C] . Alireza Hassani Najafabadi, Rui Kuai, Anna Schwendeman, Society for Biomaterials annual meeting and exposition . 2018

机译：纳米材料用于多发性硬化/实验性自身免疫性脑脊髓炎（EAE）的免疫治疗
5. Photobiomodulation with 670nm near infrared light treatment ameliorates disease severity of MOG35-55 induced experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. [D] . Muili, Kamaldeen Ayodele. 2010

机译：670nm近红外光处理的光生物调节改善了C57BL / 6小鼠MOG35-55诱导的实验性自身免疫性脑脊髓炎（EAE）的疾病严重程度。
6. Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor [O] . Yanping Wang, Steven J. Marling, Jinge G. Zhu, 2012

机译：小鼠实验性自身免疫性脑脊髓炎（EAE）的发展需要维生素D和维生素D受体
7. Kinin B(2) receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice [O] . Santos Adriana C. dos, Roffe Ester, Arantes Rosa M. E., 2008

机译：激肽B（2）受体调节趋化因子CCL2和CCL5的表达并调节小鼠实验性自身免疫性脑脊髓炎（EAE）中的白细胞募集和病理

Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor

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