Combination Chemotherapy Using Carboplatin (JM-8) and Etoposide (JET Therapy) for Recurrent Malignant Gliomas: A Phase II Study

K. Watanabe; H. Kanaya; Y. Fujiyama; P. Kim

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Combination Chemotherapy Using Carboplatin (JM-8) and Etoposide (JET Therapy) for Recurrent Malignant Gliomas: A Phase II Study

机译：卡铂（JM-8）和依托泊苷（JET治疗）联合化疗治疗复发性恶性胶质瘤的II期研究

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Background: To study efficacy and safety of chemotherapy using carboplatin (JM-8) and etoposide (“JET” therapy) for the treatment of recurrent malignant glioma, a phase II study was conducted. Tumour control, survival time, and toxicity/side effects were assessed in patients with recurrent malignant glioma which failed to respond to a postoperative combined auxiliary therapy comprising of IFN-β, ACNU and radiation.

机译：背景：为了研究使用卡铂（JM-8）和依托泊苷（“ JET”疗法）化疗治疗复发性恶性神经胶质瘤的疗效和安全性，进行了II期研究。对复发性恶性神经胶质瘤患者的肿瘤控制，生存时间和毒性/副作用进行了评估，这些患者对包括IFN-β，ACNU和放疗的术后联合辅助治疗无效。

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来源
《Acta Neurochirurgica》 |2002年第12期|1265-1270|共6页
作者
K. Watanabe; H. Kanaya; Y. Fujiyama; P. Kim;
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作者单位

Department of Neurosurgery Dokkyo University School of Medicine Mibu Tochighi Japan;

Department of Neurosurgery Dokkyo University School of Medicine Mibu Tochighi Japan;

Department of Neurosurgery Dokkyo University School of Medicine Mibu Tochighi Japan;

Department of Neurosurgery Dokkyo University School of Medicine Mibu Tochighi Japan;

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Keywords: Carboplatin; etoposide; malignant glioma; recurrence.;

机译：关键字：卡铂;依托泊苷恶性神经胶质瘤复发。;

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1. A phase II study of nimustine hydrochloride, cisplatin, and etoposide combination chemotherapy for supratentorial malignant gliomas. [J] . Beppu T, oba.tao.go.jp, Yoshida Y, Journal of neuro-oncology. . 2000,第3期

机译：盐酸尼莫斯汀，顺铂和依托泊苷联合化疗用于幕上恶性神经胶质瘤的II期研究。
2. Bevacizumab and etoposide combination chemotherapy in patients with recurrent malignant gliomas who failed bevacizumab [J] . Beverly D. Fu, Mark E. Linskey, Daniela Annenelie Bota Drugs and Therapy Studies . 2012,第1期

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3. Concurrent accelerated hyperfractionated radiation therapy and carboplatin/etoposide in patients with malignant glioma: long-term results of a phase II study. [J] . Jeremic B, Shibamoto Y, Grujicic D, Journal of neuro-oncology. . 2001,第2期

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6. Metronomic chemotherapy with daily oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study [O] . D A Reardon, A Desjardins, J J Vredenburgh, 2009

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Combination Chemotherapy Using Carboplatin (JM-8) and Etoposide (JET Therapy) for Recurrent Malignant Gliomas: A Phase II Study

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