Protein microarrays are coming of age, and the development of specialized technologies is extending their high-throughput capabilities. Michael Eisenstein reports. Like the younger child who has had an older sibling to 'soften up' his or her parents and make life a little easier, protein microarrays have benefited from lessons learned during the noisy adolescence of DNA microarrays. "Intellectually, the assays are identical to DNA microarrays," says microarray pioneer Mark Schena, visiting scholar at TeleChem International in Sunnyvale, California. "The basic tenets of miniaturization, automation and parallelism all hold for DNA and protein."
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