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Egg shortage hits race toclone human stem cells

机译:鸡蛋短缺袭击了克隆人类干细胞的竞赛

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摘要

US stem-cell researchers are calling for changes to state laws that prohibit compensating women who donate eggs for research. The laws, in leading stem-cell research states such as Massachusetts and California, are crippling the promising field of 'therapeutic cloning' that could produce useful embryonic stem-cell lines for studying various human diseases, they say. Therapeutic cloning involves transferring the nucleus from an adult human cell into a human egg with the intent of creating stem cells from the resulting embryo. Such cells could potentially serve as a therapy genetically matched to the person who donated the adult cell. Although no one has yet derived these cells, one group has now reported creating cloned human embryos in this way. But the procedure uses many eggs. Researchers say that because many states do not allow women to be paid for their egg donation, potential donors are put off and choose lucrative fertility clinics instead.
机译:美国干细胞研究人员呼吁改变州法律,禁止赔偿捐卵的女性进行研究。他们说,在马萨诸塞州和加利福尼亚州等领先的干细胞研究州,这项法律正在破坏有前途的“治疗性克隆”领域,该领域可能产生有用的胚胎干细胞系,用于研究各种人类疾病。治疗性克隆涉及将核从成年人类细胞转移到人卵中,目的是从所得胚胎中产生干细胞。此类细胞可能会成为与捐赠该成年细胞的人基因匹配的疗法。尽管还没有人衍生出这些细胞,但现在有一组报告称以这种方式创建了克隆的人类胚胎。但是程序使用许多鸡蛋。研究人员说,由于许多州不允许为捐献卵子的妇女付款,因此潜在的捐助者被推迟,而选择利润丰厚的生育诊所。

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  • 来源
    《Nature》 |2008年第7197期|p.828-829|共2页
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  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
  • 关键词

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