Intermolecular C-N Addition of Amides and S-N Addition of Sulfinamides to Arynes

摘要

The addition of H-X bonds(X=N,O,and S)to arynes to construct a new carbon-heteroatom bond is well-known.Recently,the Pd-catalyzed insertion of arynes into Si-Si,Sn-Sn,and C-Sn bonds has been reported.While there are examples of the transition-metal-free insertion of arynes into C-C,S-S,and Te-Te bonds,there is only one example of the transition-metal-free insertion of an aryne into a polarized heteroatom-containing bond,namely,the C-N sigma-bond of urea.Herein,we report a novel,transition-metal-free,intermolecular C-N addition of amides and S-N addition of sulfinamides to arynes under very mild reaction conditions.