Simple and Efficient Synthesis of Substituted 2-Pyrrolidinones,2-Pyrrolones,and Pyrrolidines from Enaminones of Baylis-Hillman Derivatives of 3-Isoxazolecarbaldehydes

摘要

The enaminones,generated from derivatives of appropriately substituted Baylis-Hillman adducts of 3-isoxazolecarbal-dehydes,undergo intramolecular ring-closure reactions to afford substituted 2-pyrrolidinones,1,5-dihydro-2-pyrrolo-nes,and N-substituted pyrrolidines in good yields.