Epidemiology and molecular typing of an outbreak of tuberculosis in a hostel for homeless men

摘要

Aim-To investigate a possible outbreak of tuberculosis in a hostel for homeless men using IS6110 profiling, a polymerase chain reaction (PCR) based fingerprinting tech- nique. Methods-Eight cass of tuberculosis Were diagnosed in residents of the hostel Over a period of 28 months. To provide Epidemiological data, a heminested in- Verse PCR (HIP) assay targeting the Insertion sequence IS6110 together with Its upstream fanking region was used to Fingerprint the eight isolates of M tuber- Culosis under investigation.