Decreased expression of pSTAT, IRF-1 and DAP10 signalling molecules in peripheral blood lymphocytes of patients with metastatic melanoma

Martinovic Katarina Mirjacic; Srdic-Rajic Tatjana; Babovic Nada; Dzodic Radan; Jurisic Vladimir; Konjevic Gordana

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Decreased expression of pSTAT, IRF-1 and DAP10 signalling molecules in peripheral blood lymphocytes of patients with metastatic melanoma

机译：转移性黑色素瘤患者外周血淋巴细胞中pSTAT，IRF-1和DAP10信号分子的表达降低

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Aims As numerous signalling molecules regulate effector functions of peripheral blood lymphocytes (PBLs) that have an important anti-tumour activity, the aim of this study was to analyse their level in patients with metastatic melanoma (MM) compared with healthy controls (HCs).

机译：目的由于许多信号分子调节具有重要抗肿瘤活性的外周血淋巴细胞（PBL）的效应子功能，因此本研究的目的是分析与健康对照（HCs）相比，转移性黑素瘤（MM）患者的水平。

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来源
《Journal of Clinical Pathology》 |2016年第4期|300-306|共7页
作者
Martinovic Katarina Mirjacic; Srdic-Rajic Tatjana; Babovic Nada; Dzodic Radan; Jurisic Vladimir; Konjevic Gordana;
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作者单位

Inst Oncol & Radiol Serbia, Dept Expt Oncol, Belgrade, Serbia;

Inst Oncol & Radiol Serbia, Dept Expt Oncol, Belgrade, Serbia;

Inst Oncol & Radiol Serbia, Dept Med Oncol, Belgrade, Serbia;

Inst Oncol & Radiol Serbia, Surg Oncol Clin, Belgrade, Serbia|Univ Belgrade, Sch Med, Belgrade, Serbia;

Univ Kragujevac, Fac Med Sci, POB 124, Kragujevac 34000, Serbia;

Inst Oncol & Radiol Serbia, Dept Expt Oncol, Belgrade, Serbia|Univ Belgrade, Sch Med, Belgrade, Serbia;

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收录信息美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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正文语种 eng
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1. Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients [J] . Diana L Simons, Gerald Lee, John M Kirkwood, Journal of Translational Medicine . 2011,第1期

机译：黑色素瘤患者大剂量干扰素治疗后外周血淋巴细胞中的干扰素信号传导模式可预测临床结果
2. Attenuated in vitro effects of IFN-alpha, IL-2 and IL-12 on functional and receptor characteristics of peripheral blood lymphocytes in metastatic melanoma patients [J] . Martinovic Katarina M. Mirjacic, Vuletic Ana M., Babovic Nada Lj., Cytokine . 2017,第期

机译：IFN-α，IL-2和IL-12对转移性黑素瘤患者外周血淋巴细胞功能和受体特性的体外效果
3. Pulse interleukin-2 with famotidine induces CD56+ lymphocytes in the peripheral blood of patients with metastatic melanoma or kidney cancer. [J] . Quan WD, Gagnon GA, Walker PR, Cancer biotherapy and radiopharmaceuticals . 2011,第1期

机译：带有法莫替丁的Pulse interleukin-2在转移性黑色素瘤或肾癌患者的外周血中诱导CD56 +淋巴细胞。
4. Determination of Relative Expression Levels of HLA Class-I Proteins in Peripheral Blood Lymphocytes Using Immunoprecipitationin Combination with Selected Ion Monitoring Mass Spectrometry [C] . Zhaojing Meng, Richard Apps, Greg Q. del Prete, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：用免疫沉淀素组合与选定离子监测质谱法使用免疫型拟合素血液淋巴细胞中HLA类-I蛋白的相对表达水平
5. BLyS/BAFF-R signaling pathway in human aggressive non Hodgkin's lymphoma B cell and normal peripheral blood B lymphocytes. [D] . Fu, Lingchen. 2007

机译：人侵略性非霍奇金淋巴瘤B细胞和正常外周血B淋巴细胞中的BLyS / BAFF-R信号传导途径。
6. Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients [O] . Diana L Simons, Gerald Lee, John M Kirkwood, 2011

机译：黑色素瘤患者大剂量干扰素治疗后外周血淋巴细胞中的干扰素信号传导模式可预测临床结果
7. Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients [O] . Diana L Simons, Gerald Lee, John M Kirkwood, 2011

机译：黑色素瘤患者大剂量干扰素治疗后外周血淋巴细胞中的干扰素信号传导模式可预测临床结果

Decreased expression of pSTAT, IRF-1 and DAP10 signalling molecules in peripheral blood lymphocytes of patients with metastatic melanoma

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