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Survey: the management of pregnant women with a history of excisional treatment of the uterine cervix for cervical intra-epithelial neoplasia

机译:调查:有宫颈切除术史的孕妇宫颈上皮内瘤变的处理

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The purpose of this study is to gauge the management of pregnant women with a past history of cervical excisional treatments for cervical intra-epithelial neoplasia (CIN). A postal survey of 120 consultant obstetricians and gynaecologists in the northwest of England was done. The response rate was 41.7%. Thirty-seven respondents (74%) agreed with the evidence that cervical excisional treatment increases the risk of late miscarriage, preterm labour, premature rupture of the membranes and spontaneous rupture of the membranes at term. Thirty-one (62%) think that cervical assessment during pregnancy in women who had excisional treatments is not essential, nevertheless, 72% of the respondents utilise transvaginal ultrasonography alone or in combination with other methods to assess the cervix in these women. Seventeen (34%) assess the cervix monthly and nineteen (38%) carry out variable assessments ranging between once in the first trimester and every 6–8 weeks. Thirty-one (62%) offer cervical cerclage and 28 (56%) will offer it between 13–16 weeks gestation. Twenty-four (48%) would offer preconception transabdominal cervical cerclage to at-risk women. Forty (80%) do not believe that previous excisional treatment will alter the vaginal flora and only eight (16%) perform high vaginal swabs. There is a lack of consensus and consistency in the cervical assessment for the prediction of the risk of preterm birth in women who had cervical excisional treatments for CIN. Transvaginal ultrasonography alone or in combination with other methods is the most favoured technique in cervical assessment. The majority of the respondents offer cervical cerclage. In the presence of evidence that cervical excisional treatment for CIN carries a real risk of pregnancy loss and morbidity, there is a need for an agreed and standardised strategy in cervical assessment and intervention techniques.
机译:这项研究的目的是评估对宫颈上皮内瘤样变(CIN)有宫颈切除治疗史的孕妇的治疗方法。对英格兰西北部的120位妇产科顾问医生进行了邮政调查。回应率为41.7%。三十七名受访者(74%)同意以下证据:宫颈切除术会增加流产,流产,早产,胎膜早破和足月胎膜自发破裂的风险。 31(62%)认为接受切除治疗的妇女在怀孕期间进行宫颈评估不是必需的,但是,仍有72%的受访者单独或通过其他方法结合阴道超声检查来评估这些妇女的子宫颈。十七(34%)个月评估子宫颈,十九(38%)进行可变性评估,范围从头三个月一次到每6-8周一次。有31位(62%)会提供子宫颈环扎术,而28位(56%)会在怀孕13–16周之间提供子宫颈环扎术。有二十四名(48%)会为高危妇女提供经前避孕的经腹宫颈环扎术。四十(80%)认为先前的切除治疗不会改变阴道菌群,只有八(16%)会进行高阴道拭子治疗。在接受宫颈切除术治疗CIN的妇女中,宫颈评估中对于预测早产风险的评估缺乏共识和一致性。单独或结合其他方法的阴道超声检查是宫颈评估中最受青睐的技术。大多数受访者提供宫颈环扎术。在有证据表明宫颈切除术治疗CIN确实有妊娠流产和发病风险的情况下,需要在宫颈评估和干预技术中采用公认的标准化策略。

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