Challenges in the development of next-generation antibiotics: opportunities of small molecules mimicking mode of action of host-defense peptides

Wang Minghui; Odom Timothy; Cai Jianfeng

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Challenges in the development of next-generation antibiotics: opportunities of small molecules mimicking mode of action of host-defense peptides

机译：下一代抗生素发展的挑战：模仿宿主防毒肽的作用模式的小分子机会

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来源
《Expert Opinion on Therapeutic Patents》 |2020年第6期|303-305|共3页
作者
Wang Minghui; Odom Timothy; Cai Jianfeng;
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作者单位

Univ S Florida Dept Chem 4202 E Fowler Ave Tampa FL 33620 USA;

Univ S Florida Dept Chem 4202 E Fowler Ave Tampa FL 33620 USA;

Univ S Florida Dept Chem 4202 E Fowler Ave Tampa FL 33620 USA;

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原文格式 PDF
正文语种 eng
中图分类
关键词
Antibiotics; drug resistance; host defense peptides; small molecules;

机译：抗生素;耐药;宿主防毒肽;小分子;

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1. Antimicrobial Polymers: Mimicking Amino Acid Functionality, Sequence Control and Three-dimensional Structure of Host-defense Peptides [J] . Hartlieb Matthias, Williams Elizabeth G. L., Kuroki Agnses, Current medicinal chemistry . 2017,第19期

机译：抗微生物聚合物：模拟氨基酸功能，序列控制和宿主防御肽的三维结构
2. Membrane Interactions of Host-defense Peptides Studied in Model Systems [J] . Raz Jelinek, Sofiya Kolusheva Current Protein and Peptide Science . 2005,第1期

机译：在模型系统中研究宿主防御肽的膜相互作用
3. Membrane Interactions of Host-defense Peptides Studied in Model Systems [J] . Raz Jelinek Sofiya Kolusheva Current Protein & Peptide Science . 2005,第1期

机译：在模型系统中研究宿主防御肽的膜相互作用
4. Synergy Between a Lead Proline-rich Antibacterial Peptide Derivative and Small Molecule Antibiotics [C] . Laszlo Otvos Jr, Marco Cassone, Vanessa de Olivier Inacio American Peptide Symposium . 2009

机译：富含脯氨酸抗菌肽衍生物和小分子抗生素之间的协同作用
5. Host-defense peptides enhance enteric viral infection in a small intestinal organoid model and in vivo. [D] . Wilson, Sarah Stricklin. 2015

机译：宿主防御肽可在小肠类器官模型和体内增强肠道病毒感染。
6. Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance [O] . Fernanda Guilhelmelli, Nathália Vilela, Patrícia Albuquerque, 2013

机译：抗生素开发面临的挑战：抗菌肽的各种作用机理和细菌耐药性
7. Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance [O] . Fernanda Guilhelmelli, Nathália Vilela, Patrícia Albuquerque, 2013

机译：抗生素发展挑战：抗菌肽和细菌抗性的各种作用机制

Challenges in the development of next-generation antibiotics: opportunities of small molecules mimicking mode of action of host-defense peptides

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