Arsenic tissue concentration f immature mice one hour after oral exposure to gold mine tailings

摘要

A potentially high bioavailability of arsenic in gold mine tailings from a site in northern California has been suggested by solubility studies. To help address this issue, an in vivo dosing Study was conducted using 12-day-old Swiss Webster mouse pups (n=8/group). A sample of size- Fractionated mine tailings from the site (＜20 μm particle size, 691 μg g~-1 arsenic) was prepared As an aqueous suspension and administered by gavage in a volume that provided 4 mg As/kg body Weight.