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Acute and chronic effects of ibuprofen in the mollusc Planorbis carinatus (Gastropoda: Planorbidae)

机译:布洛芬对软体动物Planorbis carinatus(Gastropoda:Planorbidae)的急性和慢性影响

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摘要

Laboratory populations of freshwater Keeled rams horn snails (Planorbis carinatus Muller, 1774) were exposed as adults to measured concentrations of ibuprofen free base (CAS number 15687-27-1) for up to 21 d using methanol (0.1 mL/L) as a carrier solvent. Under flow-through conditions, the 48 and 72h LC50 values were both 17.1 mg/L (95% confidence intervals 5.9-72.3 mg/L), while 21 d LOEC and NOEC values based on survival were >5.36 and 5.36 mg/L, respectively. Reproduction (in terms of hatching success) 21 d LOEC and NOEC values were 5.36 and 2.43 mg/L, respectively. Growth (wet weight) was the most sensitive endpoint measured at 21 d, with LOEC and NOEC values of 2.43 and 1.02 mg/L, respectively. We found P. carinatus to be amenable to laboratory culture and this preliminary study suggests that this species may have further potential as a useful molluscan model in ecotoxicology.
机译:成年期的淡水龙骨公羊蜗牛实验室种群(Planorbis carinatus Muller,1774)使用甲醇(0.1 mL / L)作为暴露于成年人的布洛芬游离碱(CAS号15687-27-1)的测定浓度达21 d。载体溶剂。在流通条件下,48h和72h LC50值均为17.1 mg / L(95%置信区间为5.9-72.3 mg / L),而基于存活率的21 d LOEC和NOEC值分别> 5.36和5.36 mg / L,分别。繁殖(就孵化成功而言)21 d LOEC和NOEC值分别为5.36和2.43 mg / L。生长(湿重)是在21天时最敏感的终点,LOEC和NOEC值分别为2.43和1.02 mg / L。我们发现南美白对虾适合实验室培养,这项初步研究表明,该物种作为生态毒理学中有用的软体动物模型可能具有进一步的潜力。

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