Acid-Suppressive Effect of Rabeprazole 5 mg and 10 mg Once Daily by 24-Hour Esophageal pH Monitoring in Patients with Non-erosive Reflux Disease in Japan: A Multicenter, Randomized, Parallel-Group, Double-Blind Pharmacodynamic Study

Kiyoshi Ashida; Yoshikazu Kinoshita; Michio Hongo

首页> 外文期刊>Digestive Diseases and Sciences >Acid-Suppressive Effect of Rabeprazole 5 mg and 10 mg Once Daily by 24-Hour Esophageal pH Monitoring in Patients with Non-erosive Reflux Disease in Japan: A Multicenter, Randomized, Parallel-Group, Double-Blind Pharmacodynamic Study

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Acid-Suppressive Effect of Rabeprazole 5 mg and 10 mg Once Daily by 24-Hour Esophageal pH Monitoring in Patients with Non-erosive Reflux Disease in Japan: A Multicenter, Randomized, Parallel-Group, Double-Blind Pharmacodynamic Study

机译：通过24小时食管pH监测每天一次的雷贝拉唑5 mg和10 mg对日本非糜烂性反流病患者的酸抑制作用：多中心，随机，平行，双盲的药理学研究

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摘要

Acid suppression induced by rabeprazole 5 mg in patients with NERD has not been reported in the literature.

机译：NERD患者中雷贝拉唑5 mg引起的酸抑制作用尚未见文献报道。

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来源
《Digestive Diseases and Sciences》 |2011年第8期|p.2333-2342|共10页
作者
Kiyoshi Ashida; Yoshikazu Kinoshita; Michio Hongo;
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作者单位

Division of Gastroenterology and Hepatology, Saiseikai Nakatsu Hospital, Osaka, Japan;

Second Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan;

Departments of Comprehensive Medicine and Psychosomatic Medicine, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba, Sendai, Miyagi, 980-8574, Japan;

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正文语种 eng
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24-hour esophageal pH monitoring; Rabeprazole; Nonerosive reflux disease; Minimal changes;

机译：24小时食管pH监测;雷贝拉唑;无腐蚀性反流病;变化最小;

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专利

1. Acid-suppressive effect of rabeprazole 5 mg and 10 mg once daily by 24-hour esophageal pH monitoring in patients with non-erosive reflux disease in Japan: a multicenter, randomized, parallel-group, double-blind pharmacodynamic study. [J] . Ashida K, Kinoshita Y, Hongo M Digestive Diseases and Sciences . 2011,第8期

机译：在日本非侵蚀性反流性疾病患者中，通过24小时食管pH监测每天一次雷贝拉唑5 mg和10 mg的抑酸作用：一项多中心，随机，平行分组，双盲药效学研究。
2. Randomised clinical trial: a multicentre, double-blind, placebo-controlled study on the efficacy and safety of rabeprazole 5 mg or 10 mg once daily in patients with non-erosive reflux disease. [J] . Kinoshita Y, Ashida K, Hongo M Alimentary pharmacology & therapeutics. . 2011,第2期

机译：随机临床试验：一项多中心，双盲，安慰剂对照研究，涉及每天5 mg或10 mg雷贝拉唑在非糜烂性反流性疾病患者中的疗效和安全性。
3. Randomised clinical trial: a multicentre, double-blind, placebo-controlled study on the efficacy and safety of rabeprazole 5?mg or 10?mg once daily in patients with non-erosive reflux disease [J] . Y. Kinoshita, K. Ashida, M. Hongo, Alimentary Pharmacology & Therapeutics . 2011,第2期

机译：随机临床试验：多中心，双盲，安慰剂对照研究，雷贝拉唑5 mg或10 mg每天1次在非糜烂性反流病患者中的疗效和安全性
4. Wavelet Decomposition for the Analysis of Esophageal Manometric Data in the Study of Gastroesophageal Reflux Disease [C] . Mani Najmabadi, Vijay K. Devabhaktuni, Mohamad Sawan, IEEE Biomedical Circuits and Systems Conference . 2007

机译：对食管反流病疾病研究中食管压力测量数据分析的小波分解
5. A Phase 1B, Double-blind, Placebo-controlled, Parallel-group, Multi-dose Study of the Pharmacodynamics of NGM282 on Colonic Transit, Bile Acid Homeostasis and Fecal Fat in Subjects with Functional Constipation [D] . Oduyebo, Ibironke. 2018

机译：1B，双盲，安慰剂控制，并行组，NGM282对结肠转运，胆汁酸痛和患者功能性便秘的粪便脂肪的药物动力学的多剂量研究
6. Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: A randomized double-blind study in urban Asia [O] . KM Fock, EK Teo, TL Ang, 2005

机译：雷贝拉唑与埃索美拉唑治疗非侵蚀性胃食管反流病：亚洲城市地区的一项随机双盲研究
7. Clinical trial: maintenance intermittent therapy with rabeprazole 20 mg in patients with symptomatic gastro-oesophageal reflux disease - a double-blind, placebo-controlled, randomized study [O] . R. FASS, B. DELEMOS, L. NAZARENO, 2010

机译：临床试验：患有rabeprazole的维持间歇性治疗20毫克患有症状胃肠道反流疾病的患者 - 一种双盲，安慰剂控制，随机研究

Acid-Suppressive Effect of Rabeprazole 5 mg and 10 mg Once Daily by 24-Hour Esophageal pH Monitoring in Patients with Non-erosive Reflux Disease in Japan: A Multicenter, Randomized, Parallel-Group, Double-Blind Pharmacodynamic Study

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