Fibroscan? probe selection for lean adults

摘要

Background and Aim Fibroscan? is used to assess fibrosis and steatosis of the liver noninvasively. The company suggests to use the S+-probe in people 75?cm and adults with a skin–liver capsule distance 75?cm in fasting state and after intake of a standardized light meal (300?kcal). Results We examined 50 volunteers (26 female, 24?±?3?years). Twenty-two participants were in the TC ≤75?cm group and 28 in TC 75?cm group. LS values with the S+-probe were 15% higher than with the M+-probe in both groups (median difference 0.6?kPa, P ?0.001). Both probes showed good agreement with minimal bias (Spearman correlation r =?0.754, P ?0.001; Interclass Correlation Coefficient 0.843, P ?0.001; Bland–Altman bias 0.6?±?0.9?kPa, linear regression r 2 ?=?0.557, P ?0.001). Intake of a light meal had no relevant influence on LS (S+- and M+-probes) or CAP measurements (M+-probe) in both groups. Conclusion Lean adults with a TC below 75?cm can be assessed with either the S+-probe or the M+-probe and may take a light meal before assessment.