Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety

摘要

Bacillus subtilis is a rod shaped, gram positive, spore producing bacterium. They are the normal floraof gastrointestinal tract of humans and it is the best characterized model organism for endosporeformation. It has the ability to withstand environmental stress, and synthesize beneficial compounds,therefore, it is recognized as a high-quality probiotic supplement. To ensure the probiotic safety andthe efficiency, we report the whole genome sequence (WGS) of Bacillus subtilis UBBS-14 strain. Thedraft genome sequence of Bacillus subtilis UBBS-14 consists of 4,048,984 bp and 4,017 genes,respectively. Bacillus subtilis UBBS-14 does not carry any antibiotic resistant genes containing plasmid,nor it contains any harmful putative virulence factors coding genes, therefore, it confirms theprobiotic safety of the respective strain at genome level.