Synthesis and Antimicrobial Activity of Some Novel Schiff Bases Containing 1,2,4-Triazole-3-thione

M. M.?ali?ir; B.Ko?y???t-kaymak?ioglu; B.?zbek; G.?tük

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Synthesis and Antimicrobial Activity of Some Novel Schiff Bases Containing 1,2,4-Triazole-3-thione

机译：含有1,2,4-三唑-3-Z-Thione的一些新型席夫碱的合成与抗微生物活性

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A series of Schiff bases(4a-j)were prepared by reacting 4-amino-5-(1-phenylethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione and substituted aromatic aldehydes. The chemical structures were confirmed by means of UV,1H NMR, IR, MS(API-ES) spectral data and elemental analysis. All the synthesized compounds were screened for their antimicrobial activity. Among the tested compounds, Schiff bases with 4-OH and 4-NO2substituent exhibited remarkable antimicrobial activity against all the tested microorganism.

机译：通过使4-氨基-5-（1-苯基乙基）-2,4-二氢-3H-1,2,4-三唑-3-倍酮和取代的芳香族醛反应制备一系列席夫碱（4A-J）。通过UV，1H NMR，IR，MS（API-ES）光谱数据和元素分析证实了化学结构。将所有合成的化合物筛选出抗微生物活性。在测试的化合物中，具有4-OH和4-NO2取代的Schiff碱对所有测试的微生物表现出显着的抗微生物活性。

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《Journal of Chemistry》 |2010年第s1期|共7页
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M. M.?ali?ir; B.Ko?y???t-kaymak?ioglu; B.?zbek; G.?tük;
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7. Synthesis and Antimicrobial Activity of Some Novel Schiff Bases Containing 1,2,4-Triazole-3-thione [O] . M. M. Çalisir, B. Koçyigit-kaymakçioglu, B. Özbek, 2010

机译：含有1,2,4-三唑-3-Z-Thione的一些新型席夫碱的合成与抗微生物活性

Synthesis and Antimicrobial Activity of Some Novel Schiff Bases Containing 1,2,4-Triazole-3-thione

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