Editorial Comment: Adjuvant Single-Dose Upper Urinary Tract Instillation of Mitomycin C After Therapeutic Ureteroscopy for Upper Tract Urothelial Carcinoma: A Single-Centre Prospective Non-Randomized Trial

摘要

This article aims to demonstrate the efficacy of mitomycin C infusion right after the ureteroscopyprocedure for ablation of urothelial carcinomas in patients submitted to kidney preservation protocol.Fifty-two patients were enrolled from April 1, 2015 to August 31, 2018, submitted to laser ablation followed by a single dose of mitomycin- (ASDM).The study was approved by the ethics committee. All patients with urothelial lesion T2 andthose in which endoscopic resection seemed to be feasible were included. Patients with bladder lesionsgreater than 3.0 cm or incomplete ablation of the upper urinary tract were excluded. The control groupwas composed of patients with mitomycin C intolerance but with similar radiological aspects.