Catalase deficiency renders remnant kidneys more susceptible to oxidant tissue injury and renal fibrosis in mice

摘要

Catalase deficiency renders remnant kidneys more susceptible to oxidant tissue injury and renal fibrosis in mice.BackgroundCatalase is one of the important antioxidant enzymes regulating the levels of intracellular hydrogen peroxide and hydroxyl radical. The effect of catalase deficiency on progressive renal fibrosis has not been fully elucidated.