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Close Relative of Human Middle East Respiratory Syndrome Coronavirus in Bat, South Africa

机译:南非蝙蝠的人类中东呼吸综合征冠状病毒的近亲

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To the Editor: The severe acute respiratory syndrome (SARS) outbreak of 2002–03 and the subsequent implication of bats as reservoir hosts of the causative agent, a coronavirus (CoV), prompted numerous studies of bats and the viruses they harbor. A novel clade 2c betacoronavirus, termed Middle East respiratory syndrome (MERS)–CoV, was recently identified as the causative agent of a severe respiratory disease that is mainly affecting humans on the Arabian Peninsula (1). Extending on previous work (2), we described European Pipistrellus bat–derived CoVs that are closely related to MERS-CoV (3). We now report the identification of a South Africa bat derived CoV that has an even closer phylogenetic relationship with MERS-CoV.
机译:致编者:2002-03年的严重急性呼吸道综合症(SARS)爆发,以及随后将蝙蝠作为病原体冠状病毒(CoV)的宿主的暗示,促使人们对蝙蝠及其所携带的病毒进行了大量研究。最近发现了一种新型的2c乙型冠状病毒,称为中东呼吸综合症(MERS)-CoV,是导致严重影响阿拉伯半岛人类的严重呼吸道疾病的病原体(1)。在之前的工作(2)的基础上,我们描述了与MERS-CoV(3)密切相关的源自欧洲蝙蝠的蝙蝠CoV。现在,我们报告鉴定出与MERS-CoV有更密切亲缘关系的南非蝙蝠衍生的CoV。

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