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Expansion of seasonal influenza vaccination in the Americas

机译:在美洲扩大季节性流感疫苗接种

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BackgroundSeasonal influenza is a viral disease whose annual epidemics are estimated to cause three to five million cases of severe illness and 250,000 to 500,000 deaths worldwide. Vaccination is the main strategy for primary prevention.MethodsTo assess the status of influenza vaccination in the Americas, influenza vaccination data reported to the Pan American Health Organization (PAHO) through 2008 were analyzed.ResultsThirty-five countries and territories administered influenza vaccine in their public health sector, compared to 13 countries in 2004. Targeted risk groups varied. Sixteen countries reported coverage among older adults, ranging from 21% to 100%; coverage data were not available for most countries and targeted populations. Some tropical countries used the Northern Hemisphere vaccine formulation and others used the Southern Hemisphere vaccine formulation. In 2008, approximately 166.3 million doses of seasonal influenza vaccine were purchased in the Americas; 30 of 35 countries procured their vaccine through PAHO's Revolving Fund.ConclusionSince 2004 there has been rapid uptake of seasonal influenza vaccine in the Americas. Challenges to fully implement influenza vaccination remain, including difficulties measuring coverage rates, variable vaccine uptake, and limited surveillance and effectiveness data to guide decisions regarding vaccine formulation and timing, especially in tropical countries.
机译:背景季节性流行性感冒是一种病毒性疾病,据估计,每年的流行病在世界范围内引起三至五百万例严重疾病,并导致25万至50万例死亡。疫苗接种是一级预防的主要策略。方法为了评估美洲的流感疫苗接种状况,分析了2008年以前向泛美卫生组织(PAHO)报告的流感疫苗接种数据。结果35个国家和地区在公共场所接种了流感疫苗卫生部门,而2004年为13个国家。 16个国家报告老年人的覆盖率从21%到100%不等;大多数国家和目标人群无法获得覆盖率数据。一些热带国家使用了北半球疫苗制剂,而另一些国家则使用了南半球疫苗制剂。 2008年,在美洲购买了约1.663亿剂季节性流感疫苗; 35个国家中有30个是通过泛美卫生组织循环基金购买疫苗的。结论自2004年以来,美洲迅速吸收了季节性流感疫苗。全面实施流感疫苗接种仍然面临挑战,包括难以测量覆盖率,可变疫苗摄入量以及有限的监测和有效性数据,无法指导有关疫苗配制和时机的决策,尤其是在热带国家。

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