ATYPICAL KAWASAKI DISEASE IN TWO INFANTS YOUNGER THAN 6 MONTHS

摘要

Two infants, a boy and a girl aged 2.5 and 5 months, respectively, were admitted to Tehran 's Children Hospital , for fever of unknown origin lasting for about two weeks. The boy presented with abdominal distention, diarrhea, irritability, pyuria, anemia, leukocytosis, thrombocytosis and raised titer of acute phase reactants. The girl presented with irritability, diarrhea and abdominal distention, Leukocytosis, thrombocytosis, anemia and elevated titer of acute phase reactants. All bacterial cultures and serological tests were negative. Cardiac echocardiography showed coronary artery aneurysm in both patients and confirmed the diagnosis of Kawasaki disease. These cases showed that atypical Kawasaki disease was often a late diagnosis and therefore should be quickly suspected in febrile young infants with abnormal inflammatory laboratory results without infection. Echocardiography is an important tool for diagnosis of atypical Kawasaki disease.