Comparison of the body pain and trauma degree between uni-portal and three-portal video-assisted thoracoscopic surgery for the treatment of lung cancer

摘要

Objective: To study the differences in the body pain and trauma degree between uniportal andthree-portal video-assisted thoracoscopic surgery for the treatment of lung cancer. Methods:A total of 108 patients with non-small cell lung cancer who received radical operation inour hospital between February 2013 and February 2016 were selected and divided into theuniportal group (n=52) who received uniportal video-assisted thoracoscopic surgery and thethree-portal group (n=56) who received three-portal video-assisted thoracoscopic surgery afterthe operation methods and related laboratory results were reviewed. Before operation and 24h after operation, the differences in serum levels of pain mediators, oxidative stress indexesand inflammation indexes were compared between the two groups of patients. Results: Beforeoperation, the differences in serum levels of pain mediators, oxidative stress indexes andinflammation indexes were not statistically significant between the two groups of patients. 24h after operation, serum pain mediators NE, DA and 5-HT levels of observation group werelower than those of control group; oxidative stress indexes MDA and O2﹣ levels were lower thanthose of control group while SOD and GSH-Px levels were higher than those of control group;inflammation indexes IL-6, IL-8, CRP and TNF-α levels were lower than those of controlgroup. Conclusion: Uniportal video-assisted thoracoscopic surgery for the treatment of lungcancer causes less surgery trauma, and patients’ postoperative pain and systemic inflammatorystress response are lighter.