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On the Morphology of the Drosophila Heart

机译:果蝇心脏的形态

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The circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e. , from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to name a few examples. In recent years, the Drosophila heart has also attracted the attention of researchers in the field of biomedicine. This development is mainly due to the fact that several genes causing human heart disease are also present in Drosophila , where they play the same or similar roles in heart development, maintenance or physiology as their respective counterparts in humans. This review will attempt to briefly introduce the anatomy of the Drosophila circulatory system and then focus on the different cell types and non-cellular tissue that constitute the heart.
机译:果蝇的循环系统代表了一种易于接受的遗传模型,其在不同水平上的分析,即从单分子到功能解剖学,为心脏发生,心脏生理学和心脏衰老的一般方面提供了新见解,仅举几个例子。近年来,果蝇的心脏也引起了生物医学领域研究人员的关注。这种发展主要是由于果蝇中也存在几种导致人类心脏病的基因,它们在心脏发育,维持或生理中的作用与人类中相应的基因相同或相似。这篇综述将试图简要介绍果蝇循环系统的解剖结构,然后重点介绍构成心脏的不同细胞类型和非细胞组织。

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