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Optimization of solid lipid nanoparticles prepared by a single emulsification-solvent evaporation method

机译:单乳化-溶剂蒸发法制备固体脂质纳米粒的优化

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This data article contains the data related to the research article?“Characterization, biorecognitive activity and stability of WGA grafted lipid nanostructures for the controlled delivery of rifampicin” (Pooja et al. 2015) . In the present study, SLN were prepared by a single emulsification-solvent evaporation method and the various steps of SLN preparation are shown in a flow chart. The preparation of SLN was optimized for various formulation variables including type and quantity of lipid, surfactant, amount of co-surfactant and volume of organic phase. Similarly, effect of variables related to homogezation, sonication and stirring processes, on the size and surface potential of SLN was determined and optimized.
机译:该数据文章包含与以下研究文章有关的数据:“ WGA接枝脂质纳米结构的特征,生物识别活性和稳定性,可控制利福平的递送”(Pooja等人,2015年)。在本研究中,SLN是通过单乳化-溶剂蒸发法制备的,流程图中显示了SLN制备的各个步骤。 SLN的制备针对各种配方变量进行了优化,包括脂质的类型和数量,表面活性剂,助表面活性剂的数量和有机相的体积。同样,确定并优化了与匀浆,超声处理和搅拌过程有关的变量对SLN尺寸和表面电势的影响。

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