Stage-14 oocytes of Drosophila melanogaster were irradiated (1000 R) and analyzed for cytological aberrations. 82% of the oocytes were classified as abnormal, most of them involving fragmented chromosomes. Extensive fragmentation of the chromosomes, as well as the lack of heterologous interchanges, demonstrates the inability of stage-14 oocytes to repair radiation-induced damage. The fact that fragments are seen in the stage-14 oocytes prepared immediately after treatment indicates a very rapid manifestation of the radiation effects.
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