摘要:ATC Agent is the core part of an air traffic operation simulation system .In order to increase the degree of completeness of its knowledge base and achieve accurate simulation of air traffic, the machine learning theory was introduced into ATC Agent model .This paper studied the relevant machine learning algorithms and presented the individual learning behav -ior of ATC Agent .Then Q-learning algorithm wasselected to model the learning behavior of ATC Agent .Thus the ATC Agent was able to obtain the optimal strategy in the process of air traffic operation simulation and improve its knowledge base of conflict resolution .The simula-tion result proved the rationality of learning behavior of the ATC Agent .%管制员Agent是空中交通运行仿真系统中的核心部分,为了提高其知识库的完备程度,做到空中交通的精确仿真,可以考虑将机器学习理论引入管制员Agent模型。研究了相关机器学习算法,提出管制员Agent的个体机器学习行为,选择Q学习算法对管制员Agent的学习行为进行建模,使管制员Agent能在空中交通运行仿真中取得最优策略,完善自身冲突解脱知识库的不足。仿真结果证明了管制员Agent学习行为的合理性。
摘要:为制备士的宁固体脂质纳米粒( S-SLN)及其冻干工艺研究,采用乳化溶剂挥发法制备S-SLN,在正交实验基础上,以S-SLN包封率为评价指标确定最优处方工艺,通过包封率变化率筛选冻干保护剂,并制成冻干粉.结果表明,最佳制备工艺为:单硬脂酸甘油酯30 mg,药物/单硬脂酸甘油酯比例为1∶10,单硬脂酸/卵磷脂比例为1∶2,泊洛沙姆浓度( F-68)为0.3%.通过冻干粉包封率变化率研究证实2%甘露醇为最佳冻干保护剂,S-SLN冻干粉为白色、质地疏松固体,表面光滑,复溶后分散良好.乳化溶剂挥发法制备士的宁固体脂质纳米粒冻干粉,工艺技术稳定可行,外观性状理想,粒径较小,包封率高,稳定性好,为后续S-SLN内外研究奠定良好的基础.%To prepare strychnine solid lipid nanoparticles ( S-SLN ) and research freeze -dried powder S -SLN was prepared through emulsion evaporation method .On the basis of orthogonal experiment , the optimal prescription craft was determined with strychnine coating rate of evaluation index .Lyophilized protective was screened through the envelopment rate study , which was produced to be freeze -dried powder .Results indicated that optimum preparation parameters were as follows:glycerin monostearate of 30 mg, the ratio of drug and glyceryl monostearate (1∶10), the ratio of monoglyceride and lecithin (1∶2); the concen-tration of F-68 was 0.3%.The envelopment rate study of lyophilized powder confirmed 2%mannitol as the best lyophilized protective .S-SLN producing was white and loose texture solid, which surface was smooth , and dispersion was good after dissolved .S-SLN was pro-duced by emulsion solvent evaporation method , which was stable and feasible .It’ s ideal ap-pearance , small particle size , high envelopment rate and good stability , which lays a good foundation for the follow-up in vivo and in vitro research of S -SLN.
摘要:环烯醚萜苷是中药玄参的重要成分之一,这类成分的不同的结构分型所对应的药理作用也不尽相同。以往的研究仅是对环烯醚萜苷类成分进行整体的生物活性的归类分析,针对环烯醚萜不同结构分型的代表性成分的生物活性进行归纳总结,对其应的药理作用及机制进行系统的总结,旨在合理应用中药玄参的合理应用以及对环烯醚萜苷类成分新的临床应用方向提供理论依据。%Iri doid glycosides are important components of Xuanshen ( crophularia ningpoensis Hemsl ) .Errant structure type in such ingredients corresponds to different pharmacological effects .Previous studies have only overall analyzed and classified iridoid glycosides ’ biologi-cal activities .In this paper , the biological activities , pharmacological effects and pharmaco-logical mechanism of iridoids glycosides in different structural type were summarized .The purpose was to reasonably use Xuanshen and provided a theoretical basis in clinical applica -tion of iridoid glycosides .
摘要:刻画了反对称矩阵空间上的保持行列式的函数的形式,受反对称矩阵空间上行列式性质的影响,分别研究了奇数阶反对称矩阵空间及偶数阶反对称矩阵空间上保行列式的函数的形式。%In this paper , the forms of determinant preserving function on anti -symmetric matrix space were described .Under the influence of the properties of determinant on anti -symmetric matrix spaces , the forms of determinant preserving function on odd and even order anti-symmetric matrices space were studied .
摘要:中药肉苁蓉是著名的补益中药,且具有一定的雌激素作用。通过查阅大量文献,从植物雌激素成分组成和药理作用、中药肉苁蓉的介绍及肉苁蓉的雌激素作用三个方面对中药肉苁蓉的雌激素作用的研究进行总结分析,为后续对其发挥雌激素作用的活性成分研究奠定基础。%Cistanche deserticola is a famous tonic traditional Chinese medicine, and has an effect of estrogen.In this paper, the estrogenic effect of Cistanche deserticola was reviewed consulting a large number of literatures.The review includes three aspects:composition and pharmacological effects of phytoestrogen, introduction of Cistanche deserticola and estrogenic effect of Cistanche deserticola.It lays a foundation for the subsequent study on active ingre-dients of estrogen effects.
摘要:This paper adopted the rice husk ash ( RHA ) to dynamic adsorbed Pb in the wastewater.The adsorption capacities were calculated and the breakthrough curves were drew to analyze the effect of Zn ( II) on the removal of Pb.In addition,Thomas Model and Yoon-Nelson Model were chosed to describe the adsorption process.It was showed that the high-er concentration of Zn ( II) existed,the lower adsorption capacity RHA had, and the break-through time occurred earlier.However,the co-existing Zn ( II) did not change the combi-nation process of Pb though it decreased the adsorption capacity of rice husk ash.%采用稻壳灰吸附柱吸附含铅废水,通过吸附量的计算及穿透曲线的绘制探讨了不同质量浓度共存锌离子对吸附过程的影响。并通过Thomas模型及Yoon-Nelson模型拟合,分析共存锌离子对吸附过程的影响。结果表明,共存锌离子质量浓度越大,稻壳灰对铅离子的吸附量越低,吸附到达平衡的时间越短,同时锌离子占据了部分吸附位点,并没有改变稻壳灰与铅离子的结合方式。
摘要:The problem of l2 -L∞ filter design for discrete-time system with Markov jump was investigated and a l2 -L∞performance criteria was proposed to guarantee the filtering er-ror systems to be stochastically admissible in this paper.The sufficient conditions for the ex-istence of l2 -L∞filter were presented based on the proposed performance criteria.The prob-lem of filter design was converted into a parameter optimization problem with linear matrix in-equality ( LMI) constraint.A numerical example was provided to illustrate the effectiveness of the proposed method.%针对时滞离散马尔科夫跳跃系统的l2-L∞滤波问题进行的研究,通过建立的l2-L∞性能准则,采用线性矩阵不等式( LMI)技术推导出l2-L∞滤波器存在的充分条件,在推导过程中引入附加矩阵,降低了滤波器的保守性。所设计的滤波器不但保证了滤波误差系统随机稳定,而且满足给定的l2-L∞性能指标。仿真算例表明所设计的滤波器是可行的。
摘要:Several feature points extraction methods such as Harris, SIFT and SURF were de-scribed.SIFT and SURF methods were mainly compared in order to find a better solution for the contradictions between extraction precision and extraction consuming time in vision navi-gation.A quadrotor verification platform integrating was built to test extraction precision and extraction consuming time of SIFT and SURF methods in the natural environment.The com-parison result shows that SURF was the suitable method which can meet the requirements of extraction precision and real time simultaneously.%针对视觉导航中存在的图像特征点提取精度与用时之间的矛盾,对几种常用的特征点提取算法( Harris, SIFT, SURF)进行了论述,并针对SIFT算法和SURF算法进行了比较,同时搭建了四旋翼验证平台,利用四旋翼实验平台,针对自然环境中的实物测试了上述两种算法的提取精度与用时,结果表明SURF算法是视觉导航中综合考虑匹配的正确率及实时性的较优选择。
摘要:This paper proposed a new method to implement the test procedure based on the obtained sample regardless of the specified equivalence limit.The proposed equivalence ref-erence value, which was similar to the p-value, could provide helpful information for under-standing the equivalent degree and making a quick decision.%提出了一种新的基于当前样本进行等效性或非劣效性检验的方案。这一方案无需对等效界限值事先指定。所提的等效参考值,非常类似于p值。它能够帮助临床试验人员更好地理解不同疗法的等效程度,进而可以快速做出决策判断。
摘要:For the defect of initial sensitive to chaotic time serial and the cumulative error will enlarge quickly while iterating prediction, this paper proposed an improved support vector machine ( SVM) method to avoid the disadvantages of long-term forecast.The SVM struc-ture was determined based on the reconstruction phase space.To reduce the accumulated er-ror, the existing SVM kernel function was improved to meet the condition which reduced the error.The closing price data of the Bao Steel stock exchange was applied to the improved model to get a better simulation result.%针对混沌时间序列对初值敏感,在迭代预测时累积误差将迅速放大的缺陷,提出一种改进的支持向量机的方法,避免这一弊端进行长期预测。在重构相空间的基础上,确定支持向量机的结构。为减小累积误差,对现有的支持向量机的核函数进行改进,使该核函数满足减小误差的条件。最后把沪市宝钢股份收盘价格的数据应用到改进的模型中,得到较好的仿真结果。
摘要:以假酸浆籽为原料,采用水提法、超声波提取法、微波提取法提取假酸浆多糖,经对各提取过程比较分析可知水提法为最优提取方法,提取条件为料液比1∶55、温度80℃、时间3 h,提取率为6.18%.将水提法得到的假酸浆多糖浓缩液通过醇沉、脱蛋白、脱色等工艺进行纯化,确定了最佳的提取纯化工艺.在最佳的条件下,醇沉后多糖的量可达80.5%,蛋白质脱除率可达70.8%,脱色率可达91.0%.%Nicandra polysaccharide was extracted from the seed of Nicandra physaloides ( L.) Gaertn by the method of water extraction, ultrasonic extraction, microwave extraction, respectively.Through comparative analysis on the extraction process, water extraction achie-ving 6.18%extraction rate was determined to be the optimal method, in which the ratio of material to liquid was 1∶55 , the extraction temperature was 80 ℃, and the extraction time was 3 h.The treatments of ethanol precipitation, deproteinization and decolorization were carried out for purifying to form the final polysaccharide.After the ethanol precipitation, the content of polysaccharide reached 80.5%, the protein removal rate reached 70.8%and the decolorization rate reached 91.0%.
摘要:为了准确探测和修复载波相位周跳,提高定位精度,利用惯性导航器件的输出结果对接收机的运动状态进行分类,根据不同运动状态时周跳发生的概率大小,并结合高次差法和多项式拟合法的不同特点,开展了高次差法和多项式拟合法的组合应用研究。在试验研究中使用TI公司的EZ-430运动开发套件获得接收机的运动状态信息,使用Unicore UB240卫星接收机实地接收导航报文,通过试验验证,本方法可以有效地提高周跳探测的准确性并修复周跳。%In order to accurately detect and repair the carrier phase cycle slips and improve positioning accuracy, this paper used the output of inertial navigation device to classify the state of the receiver’ s motion.According to the probability of cycle slip occurred in different motion state, combined with the different characteristics of high -order difference method and polynomial fitting method, the legitimate application of a combination of high -order difference method and polynomial fitting method was carried out.Used TI’ s EZ-430 sports development kit to get the motion state information of the receiver, and used Unicore UB240 satellite navigation receiver to receive navigation message packages.This method can effec-tively improve the accuracy of cycle slip detection and repair cycle slips.
摘要:针对一类构造得到的多元极值Copula,研究它的边界性质及尾部相关度量,并给出尾部相关度量的解析表达式。结果表明,若对参数加以约束,则其上尾相关系数可以表示成构成它的Copula的上尾相关系数的凸和。%According to a class of constructed multivariate extreme-values Copula, the prop-erty of its boundary and the tail dependence measure was studied.The tail dependence pa-rameter of extreme-value copula was also given.Under the condition that some parameters were confined, it showed that the upper tail dependence parameter of the constructed ex-treme-value Copula could be expressed as the covex combination of that of basic copulas.
摘要:利用E-凸集和E-凸函数的定义,研究了E-凸函数的性质,给出并证明了E-凸函数的一个充分必要条件:设集合M炒Rn ,映射E:Rn→Rn ,函数f:Rn→R和g:R→R,且g( t)=f( x+td),(其中d∈Rn),则f是E-凸函数当且仅当g是E-凸函数。并对E-凸函数的若干特征进行了研究分析,得出了E-凸函数的判别条件及其性质。%The properties of E-convex function were studied using the definition of E-con-vex sets and convex function.A necessary and sufficient condition of E-convex function was proved:let M炒Rn, mapping E:Rn→Rn, function f:Rn→R and g:R→R function, and g(t)=f(x+td) (where d∈Rn), then f is a E-convex function if and only if g is a E-convex function.And several features of E-convex functionwere studied and analyzed.The criteri-ons and properties of E-convex function were obtained.
摘要:This paper presented a new preconditioned AOR-type iterative method for solving the linear system, where coefficient matrix was an irreducible Z-matrix.And some theorems and corollaries were given to show that the new preconditioned AOR iterative method was convergence under the given condition.Numerical example verifies the validity.%对于系数矩阵为不可约的Z-矩阵的大型线性方程组,给出了一类新的预条件AOR迭代法,并证明其在给定的条件下是收敛的,数值例子证明解的有效性。
摘要:In the perspective of urban agglomerations, cities are no longer as isolated indi-viduals, but attracted together for the order demand.By designing the model, urban agglom-eration gravity of the whole country is maximized.By selecting the calculated range of urban agglomerations as self-logistics area, the center in the gravity center was built to service the urban agglomeration, the input-output ratio of investment was optimized to cover the highest user needs within minimum area and realize economies of scale for logistics services.It can reduce logistics costs, while improving the level of logistics services in the most densely area of consumer distribution.%从城市群的角度出发,各城市不再作为孤立的个体,而因为订单需求而“吸引”在一起。通过设计模型,使得全国范围内所有城市群订单引力之和最大。选取计算出的城市群为自营物流范围,以城市群引力中心分别建设城市群仓储配送中心,服务所在城市群。优化了物流投入产出比例,以最小面积的投入来覆盖最高的用户需求,实现了自营物流服务的规模效应,降低了物流成本的同时,在消费者分布最密集区域全方位提升了物流服务水平。
摘要:研究白藜芦醇对大鼠血清指标及肝指数的影响,探讨白藜芦醇对肝损伤大鼠的保护作用.将72只雄性大鼠随机分为6组,空白对照组、模型对照组、低、中、高剂量组和阳性药物对照组.连续给药30 d后称取大鼠重量,取血清分别检测血清谷草转氨酶( AST)、谷丙转氨酶( ALT)和超氧化物歧化酶( SOD)、丙二醛( MDA)含量,并测定肝指数、肾指数、脾指数.结果表明,白藜芦醇能降低大鼠血清中ALT、AST、TG的水平(P<0.05),提高了SOD的含量、降低了MDA的含量(P<0.05).说明白藜芦醇具有降低大鼠ALT、AST的作用,对肝损伤大鼠具有肝保护作用.%To study the effects of resveratrol on serum indicators and hepatic index in rats, and investigate the protective effect of resveratrol on hepatic injury rats 72 male rats were randomly divided into a blank control group,model control group, resveratrol high,middle, low dosage group and positive drug control group.After 30 days of administration, rats were weighted.The serum was collected to detect glutamic-oxaloacetic transaminase(AST),ala-nine aminotransferase(ALT), superoxide dismutase(SOD), malondialdehyde(MDA), liv-ing index,kidney index and spleen index.The results showed that Resveratrol could reduce rats serum ALT,AST,TG levels(P<0.05),increased the content of SOD,and reduced the content of MDA(P<0.05).Resveratrol has the ability decreasing rats’ ALT and AST,and the protective effect on liver injury rats.
摘要:Preparation of luteolin phospholipid complex was studied using luteolin and soy-bean lecithin as raw materials.The optimal reaction conditions were determined by single factor experiment.Luteolin and its phospholipid complex were scanned by UV and IR spec-trum to determine the solubility in water and the oil-water partition coefficient.The results showed that the target complex was produced.The high recombination rate could be got when the reaction temperature was at room temperature 20 ℃, the reaction time was 2 h, luteolin concentration was 1 mg/mL and the feed ratio was 1∶1.The solubility of phospholipids com-plex was higher than that of luteolin.Luteolin phospholipid complex improved water-solu-bility and fat-solubility of luteolin.%以木犀草素和大豆卵磷脂为原料制备木犀草素磷脂复合物,通过单因素实验确定最优反应条件.对木犀草素及其磷脂复合物进行紫外、红外光谱扫描并测定其在水中的溶解性和油水分配系数.结果表明,反应生成了目标复合物,木犀草素磷脂复合物制备的最佳工艺条件为反应温度室温20℃,反应时间2 h,木犀草素质量浓度为1 mg/mL,投料比为1∶1.磷脂复合物的溶解性高于木犀草素,木犀草素磷脂复合物改善了木犀草素的水溶性和脂溶性.
摘要:This paper used the BP neural network for the prediction of parking lot free park-ing number.In the process of the BP neural network training, used the BP momentum meth-od combined with self-adjusting learning rate to improve the basic BP neural network which was easy to appear shocking, convergence speed slowing and trapping in local minimum. The effectiveness of the improved BP neural network on the free parking number prediction was verified by simulation providing a basis for regional parking guidance.%采用BP神经网络,对停车场的空余泊位数量进行了预测,并针对BP神经网络训练过程中易震荡、收敛速度过慢和容易陷入局部最小的缺点,采用BP动量法与调节学习速率相结合的方法对其进行改进。通过仿真验证了BP神经网络对停车场空余泊位数预测的有效性,为区域的停车诱导提供了依据。
摘要:Based on coring and petrophysics experiment, the lithology in Lei 64 were studied by statistical methods and then divided into sandy micro-conglomerate and inequigranular sandstones.The sensitive log was optimized by column diagram, and the models of well log-ging cross-plot, decision tree and systematic clustering were developed to identify the two categories lithology based on the sensitive log.Through the study of the accuracy of the above three models, it was found that the accuracy of decision tree was higher than well logging cross-plot and systematic clustering.Finally two models of decision tree were used to iden-tify lithology of Lei 71 well.The integrated identification accuracy rate was more than 85%compared with actual coring.The results showed that the model of decision tree could be well used to identify lithology in sand-conglomerate reservoirs of this district.%在取心、岩石物理实验的基础上,采用统计方法对雷64区的岩性进行研究,将其分为砂质细砾岩和不等粒砂岩两大类。利用直方图法优选出识别这两大类岩性的敏感测井曲线,并且依据优选出来的敏感测井曲线,建立了用于识别砂质细砾岩和不等粒砂岩的测井响应交会图法、决策树模型、系统聚类模型。通过对上述三种模型进行精度分析,发现决策树模型的精度要高于测井响应交会图法和系统聚类模型。同时利用所建立的两种决策树模型对雷71井进行岩性识别,将识别结果与实际取心对比,发现综合判断准确率均大于85%。结果表明,给出的决策树模型可很好地用于该地区砂砾岩储层的岩性识别。
摘要:Let u∈H( D) ,φ∈S( D) ,weighted composition operator is defined as:uCφ( f) ( z)=u( z) f(φ( z) ) ,z∈D. This paper characterized the boundedness and compactness of weighted composition operators from the Bloch space and the analytic Besov spaces into the Zygmund space with‖uφk‖Z , and gave some other equivalent conditions.%设u∈H( D),φ∈S( D),复合算子的定义为:uCφ( f)( z)=u( z) f(φ( z) ),z∈D.用‖uφk‖Z 刻画该算子从Bloch空间和Besov空间作用到Zygmund空间的有界性和紧性,并给出等价条件.
摘要:通过对加权最小连接数算法的进一步改进,实现服务器负载均衡。针对该算法的改进做了周期性的权值信息收集,并对中途产生用户高峰而引起服务器过载问题进行有效解决,按照类别的不同进行统一分配任务的研究。通过对服务器资源的有效收集,进行逐一服务器权值计算和资源分类,并建立相应的数学模型等。应用CloudSim进行仿真实验,结果表明改进后的加权最小连接数调度算法具有更好的均衡性和可靠性,能更好的解决负载不均衡问题。%To achieve the purpose of the server load balance the weighted least connections algorithm was improved.The improvement of this algorithm contained two aspects.On the one hand, periodic weighting information was collected, and on the other hand, the overload problem of server visited by too many customers was solved by unified allocation of tasks in accordance with the different categories.Through the effective collection of server resources, weight calculation and resources classification can be received respectively, and at the same time the corresponding mathematical model can be established.In addition, the CloudSim simulation experiment was performed, and the results showed that least weighted connections algorithm had better balance and reliability which can better solve the load imbalance prob-lem.
摘要:延期支付信用时的库存策略得到了较多的关注,然而对提前支付信用条件下的库存策略研究较少。针对这一不足,研究了需求随机时,在单个供应商和单个零售商组成的供应链中,当供应商的对零售商提前支付给予价格折扣优惠时,零售商的最优采购策略和供应商的最优折扣策略。零售商在给定价格折扣时,确定最优的提前采购批量和总的采购批量,而供应商则根据零售商对价格折扣的反应设定最优的价格折扣策略。数值算例验证了论文的结论。%Inventory policy under delay payment has gained much attention.However, little literature is about inventory policy under advance payment.This paper dealt with the prob-lem of determining the retailer ’ s optimal ordering policy and supplier ’ s optimal cash dis-count under the conditions of stochastic demand and a single-supplier, a single-retailer supply chain.Given the cash discount rate, retailer decides the optimal total order size and advance payment order size.The supplier decided the optimal cash discount rate according to retailer’ s reflecting.Mathematical models have been derived for obtaining the optimal total and early payment quantity for retailer and optimal cash discount rate for supplier.The nu-merical examples are given to illustrate the results in the paper.
摘要:The inhibitor of apoptosis proteins ( IAPs) can be used as target for cancer diagno-sis and therapy, and its tumor role has drawn great attention.This paper provided a literature review of the progress in research of IAPs structure, function and the relationship between IAPs and tumors.It could provide some information for the application and development of IAPs.%凋亡抑制蛋白( inhibitor of apoptosis proteins,IAPs)可以作为癌症诊断和治疗的靶点,在肿瘤研究方面备受关注,就凋亡抑制蛋白的结构、功能、在肿瘤中的表达与肿瘤的关系等研究进展作一综述,为凋亡抑制蛋白的研究提供信息和思路。
摘要:采用食用菌为原料,采用微波辅助热水解提取法提取出复合多糖,并用凝胶树脂对提取液中复合多糖进行纯化.对复合多糖与锌离子配合反应及产物进行初步的探讨研究.确定最佳的反应条件为反应温度为60℃、反应时间为60 min、pH值为9.0,在此条件下,锌离子∶多糖配合比为1∶1(物质的量比).采用红外光谱对产物进行了表征.%Compound polysaccharide was extracted using microwave -assisted thermal hy-drolysis extraction method with edible fungus as raw materials and purified by Gel resin.The chelation between compound polysaccharide and zinc ion was preliminarily investigated.The optimal chelation condition was a reaction at 60 ℃, pH=9.0 for 60 min, and a molar ratio between zinc ion and polysaccharide of 1∶1.The product was characterized by infrared spec-troscopy.
摘要:采用多种深度线索获取二维视频深度,可以提高视频深度提取效果。针对运动线索,通过块匹配运动估计算法获得帧间深度信息;针对帧内线索,采用Laws滤波器提取深度特征,然后利用马尔可夫随机场模型训练获得帧内深度信息;在此基础上,提出了基于信息融合的二维视频深度提取方法。该方法首先通过计算背景和运动区域的信息熵,然后利用模式识别中的Neyman Pearson准则确定视频帧的运动区域。针对该区域,在帧内深度信息获取的基础上,融合帧间深度信息。实验结果和真实深度比较,证实了该方法的有效性。%The two-dimensional video depth can be obtained by various depth cues.The in-terframe information was obtained by motion clue based on block matching motion estimation algorithm, and multidimensional features are extracted by Laws filter.The intraframe infor-mation was obtained by Markov random field model with depth features.A depth extraction method based on information fusion was proposed.The information entropy of background and motion region was calculated, the Neyman Pearson principle in pattern recognition was used to determine motion region.According to the motion region, the depth estimation in-traframe information was combined based on interframe information.The experimental results were compared with the true depth, which have proven the effectiveness of method.
摘要:By solving the 3D compressible N-S equations, a numerical simulation of bomb-wing combination was discussed.The flow field with different jet position and different pressure ratio was researched.The flow field structure was analyzed, and the relations be-tween field interference and aerodynamic interference were studied.The results showed that in the supersonic flow field, different jet positions will bring jets zoom factor changes.With the increase of the angle between the jet position and the wing surface, the jet controlling be-comes more effective.%通过求解三维N-S可压缩方程,对弹-翼组合体的侧向喷流流场进行数值模拟。研究了不同喷口位置,不同喷流压力下的干扰流场。分析了流场结构,研究了流场干扰与气动力干扰的关系。结果表明,在超音速流场中,喷口位置的不同,会带来喷流放大因子的变化。喷口位置相对于翼偏转,即喷口与翼面的夹角增大,喷流放大因子相应增加,侧向喷流的控制效果更好。
摘要:研究了空间飞行器姿态主动控制系统的混沌控制,在非线性系统中加入Gauss白噪声以实现对该混沌系统的控制,对系统的混沌行为加以抑制,使系统稳定化。采用最大Lyapunov指数法,通过Matlab数值仿真技术,对原系统以及随机相位控制后的系统Lyapunov指数随时间的变化趋势进行观察,可以看到原系统为混沌状态,而随机相位控制后的系统混沌已被控制住。在计算最大Lyapunov指数的过程中采用了线性随机系统的Khasminskii球面坐标变换方法。此外,针对所研究的系统给出了相图,时间历程图和Pioncar e′截面图来验证所得到的结论,证实所用方法是有效的。%This paper studied the chaos control of the spacecraft attitude active control sys-tem.The method used in this paper was to add the Gaussian white noise to the system in or-der to control this chaotic system.Suppressed the chaotic behavior to make stabilization.The largest Lyapunov exponent was adopted, and got the data through the numerical simulation technology of Matlab.Through the trending of the Lyapunov exponent changing with the time of the original system and the random phase control system, found that the original behavior was chaotic, and the controlled system was stable.The method for computing the top Lya-punov exponent was based on the Khasminskii’ s formulation for linear stochastic systems.In addition, phase portraits, time evolution and Poincar e′map were plotted to confirm the ob-tained results which confirm the method was effective.
摘要:In this paper, a route choice model in time-definite distribution service was pro-posed to minimize the total cost which is composed of fixed cost of routes, transportation cost of the commodities and distribution delay cost.The model was based on multi-commodity network design model, transportation time, processing time and waiting time spent in logis-tics nodes were taken into consideration.A shortest route based simulated annealing algo-rithm was designed.Numerical tests showed the effectiveness of the model and algorithm.%在多商品网络问题的基础上考虑了商品的在途运输时间及商品在物流节点的作业时间、等待时间,建立了限时配送业务中的商品配送路径选择模型,设计了基于最短路问题的模拟退火算法,以数值试验证明了模型及算法的有效性。
摘要:为检测a-突触核蛋白(a-Synuclein)在人神经元母细胞瘤细胞(SH-SY5Y)中的表达,构建人野生型(WT)和A53T突变型a-Synuclein质粒(pEGFP-SNCA-WT和pEGFP-SNCA-A53T),经酶切鉴定无误后转染SH-SY5Y细胞,并对转染完成的细胞进行嘌呤霉素筛选,然后通过PCR法扩增转染后SH-SY5Y细胞的a-Synuclein片段,并对其进行测序,检测目的基因,运用Western blot法检测转染后SH-SY5Y细胞中a-Synuclein的表达.酶切鉴定结果表明pEGFP-SNCA-WT和pEGFP-SNCA-A53T质粒构建成功,嘌呤霉素筛选和转基因细胞a-Synuclein片段测序结果显示慢病毒表达载体能成功的整合到SH-SY5Y细胞基因组中,Western blot结果表明,转染后的SH-SY5Y细胞能成功的过表达a-Synuclein.a-Synuclein慢病毒表达载体构建成功,并且SH-SY5Y细胞作为宿主细胞能够表达a-Synuclein.为今后帕金森病( PD)体外模型的建立及帕金森病发病机制的研究奠定了基础.%To detect the expression of α-Synuclein in SH-SY5Y cells, the Wild-Type ( WT) or A53T mutantα-Synuclein lentiviral expression vector ( pEGFP-SNCA-WT and pEGFP-SNCA-A53T) was constructed, the orientation of which was confirmed by restric-tion analysis and was transfected into SHSY5Y cells, respectively.The individual stably transfected colony was subsequently selected in the presence of puromycin, and the gene from transfected SHSY5Y cells was PCR amplified and confirmed by restriction analysis and DNA sequencing.Restriction endonuclease results showed that pEGFP-SNCA -WT and pEGFP-SNCA-A53T plasmids were constructed successfully.The results from antibiotic selection and DNA sequencing showed that the lentiviral vector can be integrated into the ge-nome of SH-SY5Y cell successfully.Western blot assay showed that a-Synuclein could be overexpressed in the transfected SHSY5Y cells successfully.Wild-Type or A53T mutant a -Synuclein lentiviral expression vector was constructed successfully and SH-SY5Y can ex-press a-Synuclein as host cells.This paper lay the foundation for the establishment of Par-kinson’ s disease ( PD) model in vitro and the research on the pathogenesis of PD.