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首页> 外文期刊>Przeglad Dermatologiczny >An asymptomatic pedunculated nodule on the scalp: nodular hidradenoma
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An asymptomatic pedunculated nodule on the scalp: nodular hidradenoma

机译:头皮上无症状的带蒂结节:结节性淋巴结瘤

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Hidradenoma is a relatively rare tumor of appendageal origin. It is clinically characterized by a slow-growing dermal nodule and histologically by well-circumscribed dermal epithelial lobules composed of polygonal clear cells and small darker cells. Pedunculated type and ulceration are rare in hidradenoma. Here, we report a case of a nodular hidradenoma, pedunculated variety, affecting the scalp in a male patient. A case of 25-year-old man presented with an asymptomatic solitary nodule on the scalp. It had begun as an asymptomatic papule 1 year ago, gradually progressing to reach its present size of 1 × 2 cm. Occasional history of serous discharge from the nodule was noted since 3 months. On examination, a single, pedunculated, flesh-colored, non-tender, firm nodule was seen (fig. 1). The surface of the nodule was lobulated with a few crusted erosions. His general physical examination was normal. There was no regional lymphadenopathy. Excisional biopsy was done and sent for histopathological examination. Light microscopic examination revealed a well-circumscribed tumor in the dermis showing a connection to the epidermis focally. Tumor tissue was arranged in lobules separated by fibrovascular septa (fig. 2). Within the lobules, tubular lumina of various sizes, cystic spaces and many proliferating blood vessels were noted. Individual tumor cells were round to polygonal with round to oval nuclei, fine chromatin, inconspicuous nucleoli and abundant eosinophilic to clear cytoplasm (fig. 3). Mucinous material was noted in a few cystic spaces. Hidradenoma is a rare benign adnexal neoplasm that differentiates towards the eccrine and apocrine apparatus [1]. It is also known as nodular hidradenoma, nodulocystic hidradenoma and acrospiroma. It can occur at all ages, with female preponderance. There is no site predilection [2]. It is sub-divided into two types: apocrine (clear cell hidradenoma) and eccrine (poroid) differentiation. Clear cell hidradenoma is the most common type. Clinically it presents as a slow-growing, asymptomatic, solitary, freely mobile and firm dermal nodule. The lesions may be flesh-colored, red, blue or brown in color. Hidradenomas may be solid or cystic in varying proportions. Uncommonly they are pedunculated like the index case or ulcerated [3]. Local recurrences are common but malignant transformation is very rare [2]. Histopathologically, it is characterized by a well-circumscribed, encapsulated nodular,...
机译:汗腺瘤是一种相对罕见的阑尾起源的肿瘤。在临床上,其特征是真皮结节的生长缓慢,并且在组织学上,其特征是由多边形透明细胞和较暗的小细胞组成的界限分明的真皮上皮小叶。带蒂的类型和溃疡在汗腺瘤中很少见。在这里,我们报告了一例结节状水肿瘤,有蒂的变种,影响了男性患者的头皮。一例25岁男子在头皮上出现无症状的孤立性结节。 1年前开始为无症状丘疹,逐渐发展至目前的大小为1×2 cm。自3个月以来,偶有结节浆液性分泌物的病史。检查时,观察到一个有蒂的,肉色的,不嫩的结实的结节(图1)。结节的表面有少量结壳状的侵蚀。他的一般身体检查正常。没有局部淋巴结肿大。切除活检并送去进行组织病理学检查。光学显微镜检查发现真皮中有一个界限清楚的肿瘤,显示出与表皮的局部联系。肿瘤组织排列在被纤维血管间隔隔开的小叶中(图2)。在小叶内,注意到各种大小的管状腔,囊性间隙和许多增生的血管。单个肿瘤细胞呈圆形至多边形,核圆形至卵圆形,染色质细,核仁不起眼,嗜酸性粒细胞丰富,可清除细胞质(图3)。在少数囊性空间中发现粘液物质。汗腺腺瘤是一种罕见的良性附件肿瘤,可向内分泌和外分泌器官分化[1]。它也被称为结节性汗腺瘤,结节性囊状汗腺瘤和肢端螺旋体瘤。它可以在所有年龄段的女性中占主导地位。没有站点偏爱[2]。它分为两种类型:顶分泌细胞(透明细胞淋巴瘤)和内分泌细胞(类孔)分化。透明细胞淋巴瘤是最常见的类型。临床上表现为缓慢生长,无症状,孤立,可自由移动且坚固的真皮结节。病变可能是肤色,红色,蓝色或棕色。角膜瘤可为固体或囊性,比例不同。它们不常见,像索引病例一样有蒂或溃疡状[3]。局部复发很常见,但恶性转化很少见[2]。从组织病理学上讲,它的特征是边界清楚,包裹的结节状结节。

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