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Anthropometric measures as predictors for the occurrence of insulin resistance among obese Jordanians

机译:人体测量学指标预测肥胖约旦人中胰岛素抵抗的发生

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A total of 210 overweight and obese participants were recruited to investigate the association between various obesity parameters with insulin resistance (IR) in Jordanians. Weight, height, waist circumference (WC) and hip circumference were measured, and the corresponding body mass index (BMI), waist to hip ratio (WHR), and waist to height ratio (WHtR) were calculated. HOMA-IR was calculated from the corresponding fasting blood sugar and plasma insulin levels for each participant. The correlation as well as the prediction ability of obesity parameters for the occurrence of insulin resistance was evaluated statistically. Pearson and point-biserial correlation coefficients revealed that only BMI, WC and WHtR correlated with insulin resistance. However, the strength of correlation appeared to be gender-dependent. Logistic regression and ROC curve analysis showed that BMI is the best parameter to predict insulin resistance in the male population followed by WHtR. In females however, WHtR appeared to be a better classifier than BMI. In conclusion, BMI and WHtR were found to be the most significant obesity parameters for predicting insulin resistance in Jordanians male and female populations, respectively.
机译:总共招募了210名超重和肥胖参与者,以调查约旦人中各种肥胖参数与胰岛素抵抗(IR)的关系。测量体重,身高,腰围(WC)和臀围,并计算相应的体重指数(BMI),腰围与臀围比例(WHR)和腰围与身高比例(WHtR)。从每个参与者的相应空腹血糖和血浆胰岛素水平计算HOMA-IR。统计评估肥胖参数对胰岛素抵抗发生的相关性和预测能力。 Pearson和点-双序列相关系数显示,只有BMI,WC和WHtR与胰岛素抵抗相关。但是,相关的强度似乎取决于性别。 Logistic回归和ROC曲线分析表明,BMI是预测男性人群胰岛素抵抗的最佳参数,其次是WHtR。然而,在女性中,WHtR似乎比BMI更好的分类。总之,发现BMI和WHtR分别是预测约旦男性和女性人群胰岛素抵抗的最重要的肥胖参数。

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