Therapeutic Effect of Three-Dimensional Conformal Radiotherapy Combined with Tegafur Gimeracil and Oteracil Potassium in the Treatment of Locally Advanced Esophageal Cancer

摘要

Objective: To observe the therapeutic effect of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil and Oteracil Potassium in the treatment of locally advanced esophageal cancer. Method: The patients with locally advanced esophageal cancer admitted to our hospital were randomly divided into observation group and control group. The control group was treated with three-dimensional conformal radiotherapy alone; the observation group, three-dimensional conformal radiotherapy combined with tegafur was used. Result: In the observation group, the patient’s disease control rate was 89.74%, and in the control group, the patient’s disease control rate was 71.79%. The results of the two groups were compared and the difference was statistically significant (p < 0.05). In the observation group, the patient’s leukopenia rate was 38.46%, the thrombocytopenia rate was 35.90%, the incidence of nausea and vomiting was 53.85%, and the quality of life was (85.20 ± 1.59) points. There was no significant difference (p > 0.05) compared with the control group. The local recurrence rate of the observation group was 10.26%, and the difference was significant compared with the control group (p < 0.05). Conclusion: The treatment of locally advanced esophageal cancer by three-dimensional conformal radiotherapy combined with Tegafur Gimeracil and Oteracil Potassium treatment can effectively improve the control rate of the disease, and its clinical application value is very significant.