Importance of Prandial Glucose Regulation in the Management of Cardiovascular Complications in Type 2 Diabetes Mellitus

摘要

There is a worldwide epidemic increase in the number of type 2 diabetes (T2DM) patients who frequently associate with cardiovascular disease (CVD). There are data suggesting that glycemic control does not substantially reduce CVD risk but hyperglycemia increases the risk of CVD. This apparent paradox could be explained by the role of post-prandial hyperglycemia in the pathogenesis of cardiovascular complications in T2DM. There is numerous evidences, both experimental and clinical, for this association but controversies on this topic persist. The aim of this paper was to review the current literature regarding the role of postprandial glucose in the genesis of CVD in T2DM.