首页> 外文期刊>Revista Brasileira de Anestesiologia >Reabilita??o funcional e analgesia com uso de toxina botulínica A na síndrome dolorosa regional complexa tipo I do membro superior: relato de casos
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Reabilita??o funcional e analgesia com uso de toxina botulínica A na síndrome dolorosa regional complexa tipo I do membro superior: relato de casos

机译:肉毒杆菌毒素A在上肢I型复杂区域性疼痛综合征中的功能性康复和镇痛:病例报告

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BACKGROUND AND OBJECTIVES: Functional inability of the affected limb is often added to alodynia and hyperalgesia in Complex Regional Pain Syndrome (CRPS) type I. Two CRPS cases are reported in which botulinum toxin A as coadjuvant drug has contributed to motor and functional recovery of the affected limb. CASE REPORTS: Two CRPS type I patients were initially evaluated for upper limb pain control. Both were unable to open the hand and referred pain intensity by numeric analog scale (NAS) of 10 at rest or when hand and fingers were passively manipulated. A sequence of 5 weekly ipsilateral stellate ganglion blockade with clonidine and lidocaine was started. Simultaneously, during the third stellate ganglion blockade, 75 Ul botulinum toxin A was administered to flexor muscles of phalanges and wrist joint. One week after botulin toxin A administration patients presented phalanges and wrist relaxation, reported easy passive physical therapy and pain was classified as 2 (NAS) at passive manipulation. At stellate ganglion blockade sequence completion patients were submitted to 3 weekly regional intravenous clonidine, lidocaine and parecoxib. At 8 months evaluation patients presented 70% and 80% motor and functional recovery of the affected limb. CONCLUSIONS: Muscular botulin toxin A has resulted in movement improvement of the affected limb and analgesia, favoring functional recovery.
机译:背景与目的:I型复杂区域疼痛综合症(CRPS)常常使患肢的功能不全加到痛觉过敏和痛觉过敏中。据报道有2例CRPS病例,肉毒杆菌毒素A作为辅助药物促进了运动和功能恢复。患肢。病例报告:最初评估了两名CRPS I型患者的上肢疼痛控制。在静止或被动操作手和手指时,两个人都无法张开手并以10的数字模拟量表(NAS)表示疼痛强度。开始使用可乐定和利多卡因进行每周5次同侧星状神经节阻滞的序列。同时,在第三次星状神经节阻滞期间,向趾骨和腕关节的屈肌施用了75μl的U1肉毒毒素A。肉毒杆菌毒素A给药一周后,患者出现指骨和腕部松弛,报告称容易进行被动物理治疗,在被动操作时疼痛分为2级(NAS)。在星状神经节阻滞序列完成时,患者接受每周3次区域静脉注射可乐定,利多卡因和帕瑞昔布治疗。在8个月的评估中,患者的患肢恢复了70%和80%的运动和功能恢复。结论:肌肉肉毒杆菌毒素A导致患肢和止痛的运动改善,有利于功能恢复。

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