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5-Acetyl-3-amino-4-(4-meth--oxy-phen-yl)-6-methyl-thieno[2,3-b]pyridine-2-carbo-nitrile

机译:5-乙酰基-3-氨基-4-(4-甲基-氧-苯基-基)-6-甲基-噻吩并[2,3-b]吡啶-2-碳腈

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摘要

The asymmetric unit of the title compound, C18H15N3O2S, comprises two independent mol-ecules, which differ primarily in the orientations of the acetyl and?p-anisyl substituents, each being rotated in opposite directions from the mean plane of the pyridine ring. The major feature of the mol-ecular packing is the formation of a two-dimensional network parallel to the (110) plane, being mediated by amine-N—H?O(carbon-yl) hydrogen bonds involving one amine H atom of each independent mol-ecule. The remaining amine-H atoms form significantly weaker N—H?O(meth-oxy) inter-actions.
机译:标题化合物C18H15N3O2S的不对称单元包含两个独立的分子-小分子,其主要区别在于乙酰基和β-茴香基取代基的方向,每一个都从吡啶环的平均平面沿相反的方向旋转。分子堆积的主要特征是形成平行于(110)平面的二维网络,该网络由涉及每个胺H原子的胺-NH-O(碳-基)氢键介导独立分子。剩余的胺-H原子形成明显较弱的NH-O(甲氧基)相互作用。

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