11β-Hy-dr-oxy-medroxyprogesterone

摘要

The title compound, C22H32O4, a fungal-transformed metabolite of medroxyprogesterone, comprises one cyclo-hexa-none ring, two cyclo-hexane rings and one cyclo-pentane ring fused together. The cyclo-hexa-none ring has a half-chair conformation, while the cyclo-hexane rings possess chair conformations and the cyclo-pentane ring has a twisted conformation on the fused C—C bond. In the crystal, mol-ecules are linked by strong O—H?O and also C—H?O hydrogen bonds, creating a two-dimensional network parallel to (10-1).