Esophageal involvement in progressive systemic sclerosis

摘要

Progressive systemic sclerosis (PSSc) is a chronic disease of unknown etiology characterized by progressive, abnormal accumulation of fibrous tissue in the skin and many organs. Characteristically, there is induration and thickening of the skin (scleroderma), abnormalities involving muscles, joints, and viscera. The first description was likely by William and Robert Watson in 1754.