Low-temperature precipitation for the determination of residual organotin compounds in plant oil using dispersive-solid phase extraction and gas chromatography-mass spectrometry

摘要

Considerable numbers of organotin compounds, which are widely used in peoplea€?s lives, have serious toxic effects to human health. In this paper, a simple, low-cost method for the simultaneous determination of four organotins in plant oil samples by gas chromatography-mass spectrometry (GC-MS) has been established for the first time. The method uses dispersive-solid phase extraction (d-SPE) clean-up after a low-temperature precipitation procedure, in situ derivatization with NaBEt4 and liquida€“liquid extraction (LLE). The relevant experimental variables influencing the whole results were optimized; a good accuracy and precision were attained under the optimal conditions. The average recoveries obtained for analytes were in the range of 75.6a€“114.9% with a relative standard deviation (RSD) of 3.9a€“12.6%, and the limits of detection for each organotin ranged between 0.19 and 0.33 ??g kga?’1. Finally, these four organotins in different oil samples were detected using this method, which demonstrated the feasibility of our developed method in this study.